Polypeptide MELO3C002149P1
Accession: MELO3C002149P1
Name: MELO3C002149P1
Description: Similar to Uncharacterized protein yeiA (Escherichia coli (strain K12)) (uniprot_sprot:sp|P25889|YEIA_ECOLI)
Sequence:
>MELO3C002149P1 Similar to Uncharacterized protein yeiA (Escherichia coli (strain K12)) (uniprot_sprot:sp|P25889|YEIA_ECOLI) MASFNLTQFRTKNPIPNLALNPSRTGLTRPTRLGFRVVASGEPQAEPDLSVTVNGLNMPNPFVIGSGPPGTNYTVMKRAF DEGWGAVIAKTVSLDAAKVINVTPRYARLRADSNGSAKGQIIGWENIELISDRPLETMLKEFKQLKEEYPDRILIASIME EYNKAAWEELIDRVEQTGVDAFEINFSCPHGMPERRMGAAVGQDCALLEEVCGWINAKATIPVWAKMTPNITDISQPARV ALKSGCEGIAAINTIMSVMGIDLKTLRPEPCVEGYSTPGGYSSKAVHPIALGKVLSIAKMMKAEFNDGDYSLSGIGGVEA GGDAAEFILLGANTVQVCTGVMMHGYGLVKKLCAELQDFMKLHNFSSIEDFRGASLPYFTTHMDLVRRQREAIEQRKAVK KGLQSDKDWTGDGFVKETESMVSN*
Download fasta sequence.
Properties
These properties come from blast2go analysis
molecular_function: dihydropyrimidine dehydrogenase (NADP+) activity, dihydroorotate oxidase activity.
cellular_component: plastid.
biological_process: oxidation-reduction process, UMP biosynthetic process, 'de novo' pyrimidine base biosynthetic process.
These properties come from reactome analysis
REACTOME_REACTION: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (REACT_102856), uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (REACT_85525), uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (REACT_546), thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (REACT_92348), thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (REACT_101500), thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (REACT_89636), (S)-dihydroorotate + ubiquinone => orotate + ubiquinol (REACT_32336), uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (REACT_80891), (S)-dihydroorotate + ubiquinone => orotate + ubiquinol (REACT_89913), thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (REACT_1067), uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (REACT_98344), thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (REACT_102503).
biological_process: nucleobase, nucleoside and nucleotide metabolic process, pyrimidine base metabolic process, pyrimidine nucleoside biosynthetic process, pyrimidine nucleoside catabolic process.
REACTOME_COMPLEX: DPYD dimer [cytosol] (REACT_4541).
REACTOME_PATHWAY: Metabolism of nucleotides (REACT_28046), Pyrimidine metabolism (REACT_957), Metabolism of nucleotides (REACT_82673), Pyrimidine metabolism (REACT_87817), Pyrimidine catabolism (REACT_1023), Pyrimidine metabolism (REACT_30021), Pyrimidine catabolism (REACT_83442), Pyrimidine metabolism (REACT_32589), Pyrimidine biosynthesis (REACT_105473), Pyrimidine catabolism (REACT_32812), Metabolism of nucleotides (REACT_97332), Metabolism of nucleotides (REACT_29767), Pyrimidine biosynthesis (REACT_79272), Pyrimidine catabolism (REACT_99805), Pyrimidine metabolism (REACT_86085), Pyrimidine metabolism (REACT_90567), Pyrimidine catabolism (REACT_100711), Metabolism of nucleotides (REACT_86759), Metabolism of nucleotides (REACT_1698).
These properties come from phylome analysis
molecular_function: 4 iron, 4 sulfur cluster binding, NADP binding, flavin adenine dinucleotide binding, metal ion binding, protein homodimerization activity, electron carrier activity, protein binding, dihydropyrimidine dehydrogenase (NADP+) activity, dihydroorotate oxidase activity.
cellular_component: extrinsic to membrane, chloroplast, cytosol, cytoplasm.
biological_process: cellular response to nitrogen levels, thymidine catabolic process, uracil catabolic process, thymine catabolic process, purine base catabolic process, oxidation-reduction process, UMP biosynthetic process, 'de novo' pyrimidine base biosynthetic process.
These properties come from kegg analysis
KEGG_REACTION: 5,6-dihydro-5-fluorouracil:NADP+ (R08226), 5,6-Dihydrothymine:NADP+ (R01415), 5,6-Dihydrouracil:NADP+ (R00978).
KEGG_ORTHOLOGS: dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2] (K00207).
molecular_function: dihydropyrimidine dehydrogenase (NADP+) activity.
KEGG_MODULE: beta-Alanine biosynthesis, cytosine / uracil => beta-alanine (M00046).
KEGG_PATHWAY: Drug metabolism - other enzymes (ko00983), Pantothenate and CoA biosynthesis (ko00770).
This polypeptide in other databases
In PhylomeDB is Phy003A7L5_CUCME .
