Polypeptide MELO3C011330P1

Accession: MELO3C011330P1

Name: MELO3C011330P1

Description: Similar to Enoyl-CoA hydratase 2, peroxisomal (Arabidopsis thaliana) (uniprot_sprot:sp|Q8VYI3|ECH2_ARATH)

Sequence:

>MELO3C011330P1 Similar to Enoyl-CoA hydratase 2, peroxisomal (Arabidopsis thaliana) (uniprot_sprot:sp|Q8VYI3|ECH2_ARATH)
MAGNPSPFDPARILAHKFPETTTTYTERDVALYALGVGACGQQAVDADELKYVYNENGQEYIEVLPTFSALFILDTLSTG
LNLPGLSYDPKLLLHGQQYIELYKPLSSSGYLDNKVSLAGLHDKGKAAILEVATKSYDKKSGQLLCMNRTTLFLRGAGGF
SSSSNPFSYTNYPKDQGSAGKIPKTQPFTVYEDCTRPSQALLYRLSGDYNPLHSDPMVAKVAGFSKPILHGLCTLGFAVR
AVIKCVCKGDSSKVKRILGKFLLHVYPGETLVTEMWLEGSRVLYQTKVKERNRAVLSGYVDLNHVASSL*

Download fasta sequence.

Properties

These properties come from reactome analysis


REACTOME_REACTION: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (REACT_28823), trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (REACT_98241), 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (REACT_94022), 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (REACT_9952), 3-hydroxyhexacosanoyl-CoA + NAD+ => 3-ketohexacosanoyl-CoA + NADH + H+ (REACT_104792), 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (REACT_31730), 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (REACT_16976), (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (REACT_83211), (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (REACT_83929), (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (REACT_10065), 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (REACT_102889), 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (REACT_108955), 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (REACT_85352), 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (REACT_88510), 3-hydroxyhexacosanoyl-CoA + NAD+ => 3-ketohexacosanoyl-CoA + NADH + H+ (REACT_29995), (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (REACT_105101), 3-hydroxyhexacosanoyl-CoA + NAD+ => 3-ketohexacosanoyl-CoA + NADH + H+ (REACT_97730), trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (REACT_96877), 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (REACT_34604), 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (REACT_84136), trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (REACT_104352), trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (REACT_94709), 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (REACT_92834), (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (REACT_9967), trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (REACT_16908), (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (REACT_106598), trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (REACT_16944), 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (REACT_93513), (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (REACT_28171), 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (REACT_104004), 3-hydroxyhexacosanoyl-CoA + NAD+ => 3-ketohexacosanoyl-CoA + NADH + H+ (REACT_16971), 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (REACT_88140), 3-hydroxyhexacosanoyl-CoA + NAD+ => 3-ketohexacosanoyl-CoA + NADH + H+ (REACT_106630), (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (REACT_33370), (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (REACT_95831), 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (REACT_95150), 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (REACT_10019), (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (REACT_90995), trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (REACT_99339), trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (REACT_101938), trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (REACT_84995), 3-hydroxyhexacosanoyl-CoA + NAD+ => 3-ketohexacosanoyl-CoA + NADH + H+ (REACT_99256), (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (REACT_84012), trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (REACT_29059), trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA (REACT_33517), (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (REACT_100408), 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (REACT_109984), 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (REACT_93290).

biological_process: bile acid metabolic process, cellular lipid metabolic process, bile acid biosynthetic process, fatty acid beta-oxidation using acyl-CoA oxidase.

REACTOME_COMPLEX: HSD17B4 dimer [peroxisomal matrix] (REACT_17840).

REACTOME_PATHWAY: Synthesis of bile acids and bile salts (REACT_101474), Beta-oxidation of pristanoyl-CoA (REACT_81180), Peroxisomal lipid metabolism (REACT_94360), Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (REACT_96571), Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (REACT_28270), Peroxisomal lipid metabolism (REACT_16957), Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (REACT_28083), Beta-oxidation of pristanoyl-CoA (REACT_85427), Peroxisomal lipid metabolism (REACT_82818), Synthesis of bile acids and bile salts (REACT_82865), Beta-oxidation of pristanoyl-CoA (REACT_78524), Beta-oxidation of very long chain fatty acids (REACT_101952), Beta-oxidation of very long chain fatty acids (REACT_17062), Synthesis of bile acids and bile salts (REACT_11054), Beta-oxidation of very long chain fatty acids (REACT_102511), Metabolism of lipids and lipoproteins (REACT_81798), Beta-oxidation of pristanoyl-CoA (REACT_31512), Beta-oxidation of pristanoyl-CoA (REACT_83684), Peroxisomal lipid metabolism (REACT_98520), Metabolism of lipids and lipoproteins (REACT_22258), Peroxisomal lipid metabolism (REACT_79191), Synthesis of bile acids and bile salts (REACT_103792), Bile acid and bile salt metabolism (REACT_85920), Synthesis of bile acids and bile salts (REACT_99724), Bile acid and bile salt metabolism (REACT_81692), Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (REACT_81858), Metabolism of lipids and lipoproteins (REACT_109614), Bile acid and bile salt metabolism (REACT_94447), Beta-oxidation of very long chain fatty acids (REACT_110355), Metabolism of lipids and lipoproteins (REACT_104203), Beta-oxidation of very long chain fatty acids (REACT_86200), Bile acid and bile salt metabolism (REACT_84189), Metabolism of lipids and lipoproteins (REACT_79403), Peroxisomal lipid metabolism (REACT_81319), Beta-oxidation of very long chain fatty acids (REACT_84654), Beta-oxidation of pristanoyl-CoA (REACT_17017), Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (REACT_77758), Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (REACT_11041), Bile acid and bile salt metabolism (REACT_11040), Synthesis of bile acids and bile salts (REACT_30249), Metabolism of lipids and lipoproteins (REACT_106721), Bile acid and bile salt metabolism (REACT_96936).

These properties come from phylome analysis


molecular_function: 3R-hydroxyacyl-CoA dehydratase activity, identical protein binding, sterol binding, isomerase activity, long-chain-enoyl-CoA hydratase activity, oxidoreductase activity, sterol transporter activity, estradiol 17-beta-dehydrogenase activity, enoyl-CoA hydratase activity, 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity, protein binding, 3-hydroxyacyl-CoA dehydrogenase activity.

cellular_component: peroxisome, peroxisomal matrix.

biological_process: oxidation-reduction process, fatty acid beta-oxidation, unsaturated, even number, lipid storage, determination of adult lifespan, defense response, bile acid biosynthetic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase.

These properties come from blast2go analysis


molecular_function: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity, protein binding, 3-hydroxyacyl-CoA dehydrogenase activity.

cellular_component: peroxisomal matrix.

biological_process: fatty acid beta-oxidation using acyl-CoA oxidase.

Locations

Located in CM3.5_scaffold00014 from 4764755 to 4771113.

This polypeptide in other databases

In PhylomeDB is Phy003AB1L_CUCME .

Related features