Protein coding gene MELO3C013815
Accession: MELO3C013815
Name: MELO3C013815
Description: Similar to Guanine nucleotide-binding protein alpha-2 subunit (Glycine max) (uniprot_sprot:sp|P93163|GPA2_SOYBN)
Properties
These properties come from reactome analysis
REACTOME_REACTION: The Ligand:GPCR:Gz complex dissociates (REACT_22170), Adenylaye cyclase increases the GTPase activity of G alpha-olf (REACT_15449), G alpha (z) inhibits adenylate cyclase (REACT_19147), G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (REACT_82461), G alpha (q) auto-inactivates by hydrolysing GTP to GDP (REACT_108363), G-protein alpha subunit is inactivated (REACT_15316), Activation of PLC beta-1/4 (REACT_91086), Dissociation of the TP:G13 complex (REACT_20559), The G alpha-olf:GDP:Adenylate cyclase complex dissociates (REACT_78239), Adenylate cyclase converts ATP into cyclic AMP (REACT_15399), Dissociation of the P2Y purinoceptor 1:Gq complex (REACT_20551), G alpha (z) inhibits adenylate cyclase (REACT_93015), GRK5 sequesters activated Gq (REACT_84764), G alpha (i) inhibits adenylate cyclase (REACT_19222), G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (REACT_56), Galpha-olf:GTP binds to adenylate cyclase and activates it (REACT_80878), Galpha-olf:GTP binds to adenylate cyclase and activates it (REACT_106393), Dissociation of the PAR:Gq complex (REACT_23818), Inactive G alpha (q) reassociates with G beta:gamma (REACT_22425), Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (REACT_22424), G alpha (q) binds to Trio family RhoGEFs (REACT_19301), Adenylate cyclase increases the GTPase activity of G alpha-olf (REACT_30005), Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (REACT_22436), Inactivation of PLC beta (REACT_15301), G alpha (q) inhibits PI3K alpha (REACT_95725), G-protein alpha subunit is inactivated (REACT_31604), Activated Adenylate cyclase catalyses cAMP synthesis (REACT_80465), Olfactory Receptor - G Protein olfactory trimer complex formation (REACT_15515), Inactivation of PLC beta (REACT_31813), Dissociation of the Gi alpha:G olf complex (REACT_107224), LARG activation by G alpha 12/13 (REACT_109073), Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1 (REACT_18383), Liganded Gz-activating GPCR acts as a GEF for Gz (REACT_83698), The Ligand:GPCR:Gi complex dissociates (REACT_22239), Dissociation of the Gi alpha:G olf complex (REACT_15384), Galpha-olf:GTP binds to adenylate cyclase and activates it (REACT_15385), Inactive G alpha (i) reassociates with G beta:gamma (REACT_22335), G-protein beta-gamma subunits rebind the alpha-GDP subunit (REACT_15387), Activation of PLC beta-1/4 (REACT_98277), Dissociation of the TP:Gq complex (REACT_20658), Dissociation of Gi/o Heterotrimeric G-protein Complex (REACT_18349), G13 activation by TP receptor (REACT_79051), GRK5 sequesters activated Gq (REACT_19325), Adenylate cyclase increases the GTPase activity of G alpha-olf (REACT_15335), G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (REACT_19123), G alpha (s) activates adenylate cyclase (REACT_34695), PLC beta-mediated PIP2 hydrolysis (REACT_80473), G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (REACT_96132), The G alpha-olf:GDP:Adenylate cyclase complex dissociates (REACT_108770), PIP2 hydrolysis (REACT_87628), G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (REACT_32496), Gq activation by PAR (REACT_1430), PLC beta is activated by G alpha (q) (REACT_97105), G alpha (z) auto-inactivates by hydrolysing GTP to GDP (REACT_107730), Gz is a substrate for PKC (REACT_22249), PLC beta is activated by G alpha (q) (REACT_81799), G alpha (s) auto-inactivates by hydrolysing GTP to GDP (REACT_101520), PLC beta-mediated PIP2 hydrolysis (REACT_28636), Liganded Gz-activating GPCR acts as a GEF for Gz (REACT_33310), G alpha (s) auto-inactivates by hydrolysing GTP to GDP (REACT_110859), Gq activation by TP receptor (REACT_100888), Thrombin-activated PAR binds G-protein Gq (REACT_23902), Activated TP receptor binds G-proten Gq (REACT_20520), Activated P2Y purinoceptor 12 binds G-protein Gi (REACT_20523), Activated P2Y purinoceptor 1 binds G-protein Gq (REACT_20525), Dissociation of the P2Y purinoceptor 12:Gi complex (REACT_20630), G alpha (q) binds to Trio family RhoGEFs (REACT_86116), LARG activation by G alpha 12/13 (REACT_29492), Gq activation by P2Y purinoceptor 1 (REACT_20636), G alpha (i) auto-inactivates by hydrolysing GTP to GDP (REACT_19219), Gs activation by prostacyclin receptor (REACT_110192), The Ligand:GPCR:G12/13 complex dissociates (REACT_22264), The Ligand:GPCR:Gq complex dissociates (REACT_22263), Inactive G alpha (z) reassociates with G beta:gamma (REACT_22135), Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex (REACT_19346), GRK2 sequesters activated Gq (REACT_84415), Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (REACT_22289), Adenylaye cyclase increases the GTPase activity of G alpha-olf (REACT_31530), Liganded Gz-activating GPCR acts as a GEF for Gz (REACT_22380), Activation of PLC beta-1/4 (REACT_15402), Dissociation of the PAR:G12/13 complex (REACT_23796), Adenylate cyclase converts ATP into cyclic AMP (REACT_110346), The high affinity receptor complex binds to G-protein (REACT_15298), Adenylate cyclase increases the GTPase activity of Gi alpha (REACT_84312), G alpha (s) activates adenylate cyclase (REACT_95192), G-protein alpha subunit is inactivated (REACT_34480), Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (REACT_15291), PIP2 hydrolysis (REACT_104013), G alpha (q) auto-inactivates by hydrolysing GTP to GDP (REACT_19186), Gq activation by TP receptor (REACT_20511), G alpha (z) inhibits adenylate cyclase (REACT_88242), PIP2 hydrolysis (REACT_15353), G alpha (q) binds to Trio family RhoGEFs (REACT_91138), The receptor:G-protein complex binds GTP (REACT_15491), PLC beta-mediated PIP2 hydrolysis (REACT_960), Adenylate cyclase increases the GTPase activity of Gi alpha (REACT_15495), The receptor:G-protein complex dissociates (REACT_15336), G12/13 activation by PAR (REACT_637), G Protein trimer formation (olfactory) (REACT_15416), Activation of Gq by Muscarinic Acetylcholine Receptor M3 (REACT_18309), PLC beta is activated by G alpha (q) (REACT_19270), Activation of Phospholipase C Beta by Gq alpha (REACT_18418), Gi activation by P2Y purinoceptor 12 (REACT_20507), G alpha (z) auto-inactivates by hydrolysing GTP to GDP (REACT_19178), Activated TP receptor binds G-protein G13 (REACT_20501), G alpha (q) inhibits PI3K alpha (REACT_19172), G alpha (q) auto-inactivates by hydrolysing GTP to GDP (REACT_81664), Liganded G12/13-activating GPCR acts as a GEF for G12/13 (REACT_22370), Liganded Gi-activating GPCR acts as a GEF for Gi (REACT_34343), G-protein alpha subunit is inactivated (REACT_83403), Inactive G alpha (12/13) reassociates with G beta:gamma (REACT_22368), G alpha (z) auto-inactivates by hydrolysing GTP to GDP (REACT_95550), Activated Adenylate cyclase catalyses cAMP synthesis (REACT_30354), LARG binds plexin B1 (REACT_19360), The G alpha-olf:GDP:Adenylate cyclase complex dissociates (REACT_15547), The receptor:G-protein complex releases GDP (REACT_15549), Inactivation of PLC beta (REACT_87892), G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (REACT_105297), Opsins that act as GEFs for G alpha-t (REACT_18400), Dissociation of Gq alpha:GTP Complex from G beta:G gamma Complex (REACT_18316), Activation of Gi/o Heterotrimeric G Proteins by Alpha Adrenergic Receptors Alpha-2A/2C (REACT_18311), Adenylaye cyclase increases the GTPase activity of G alpha-olf (REACT_108825), Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (REACT_22150), GRK2 sequesters activated Gq (REACT_19213), GRK5 sequesters activated Gq (REACT_100374), LARG activation by G alpha 12/13 (REACT_19158), Adenylate cyclase converts ATP into cyclic AMP (REACT_104211), Thrombin-activated PAR binds G-protein G12/13 (REACT_23839), p115-RhoGEF activation of Rac1 (REACT_1214), G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (REACT_15435), Liganded Gi-activating GPCR acts as a GEF for Gi (REACT_15538), G13 activation by TP receptor (REACT_20567), G alpha (z) auto-inactivates by hydrolysing GTP to GDP (REACT_82856), p115-RhoGEF activation of Rac1 (REACT_33674), G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (REACT_78069).
biological_process: synaptic transmission, transmembrane transport, cellular response to glucagon stimulus, inhibition of adenylate cyclase activity by G-protein signaling pathway, regulation of insulin secretion, energy reserve metabolic process, water transport, blood coagulation, platelet activation, activation of adenylate cyclase activity by G-protein signaling pathway.
REACTOME_COMPLEX: TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (REACT_20944), ADP:P2Y purinoceptor 1:G-protein Gq (inactive) [plasma membrane] (REACT_21114), G-protein alpha (i): GTP [plasma membrane] (REACT_19580), Opioid:MOR:G-protein complex [plasma membrane] (REACT_15585), Activated PLC beta 1/4 [plasma membrane] (REACT_15568), G-protein alpha (q):GRK2 [plasma membrane] (REACT_19587), ADP:P2Y purinoceptor 12:G-protein Gi (active) [plasma membrane] (REACT_20967), Heterotrimeric G-protein G12 (inactive) [plasma membrane] (REACT_5832), G-protein alpha:GDP [plasma membrane] (REACT_17952), Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (REACT_22589), PLC beta:G alpha (q/11) [plasma membrane] (REACT_17363), Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (REACT_23190), TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (REACT_20867), (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (REACT_15896), G-protein alpha (z):GDP [plasma membrane] (REACT_20097), Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (REACT_22602), G Protein Trimer Complex (olfactory) [plasma membrane] (REACT_15768), Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (REACT_5130), G-protein alpha (12):GTP [plasma membrane] (REACT_5043), Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (REACT_22813), G-protein alpha (i):GDP [plasma membrane] (REACT_19806), G alpha-olf:GTP [plasma membrane] (REACT_16015), G protein-GTP [plasma membrane] (REACT_15745), G(q) alpha: GTP Complex (pancreatic beta cell) [plasma membrane] (REACT_18564), (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (REACT_15996), G-protein i/o alpha:GTP:G-protein beta:G-protein gamma Complex [plasma membrane] (REACT_18596), G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (REACT_19914), G protein alpha:GTP complex [plasma membrane] (REACT_17389), G-alpha(t)-GTP [plasma membrane] (REACT_18710), G-protein alpha (q/11):PI3K alpha [plasma membrane] (REACT_20202), G-protein i/o alpha:GDP:G-protein beta:G-protein gamma Complex [plasma membrane] (REACT_18744), Phospholipase C Beta: G(q) Complex [plasma membrane] (REACT_18449), G-protein alpha (q/11):GDP [plasma membrane] (REACT_3769), ADP:P2Y purinoceptor 12:G-protein Gi (inactive) [plasma membrane] (REACT_21024), G-protein alpha (13):GDP [plasma membrane] (REACT_17165), Heterotrimeric G-protein G12 (active) [plasma membrane] (REACT_5245), Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (REACT_23035), G(q) alpha:GTP: G beta: G gamma Complex (pancreatic beta cell) [plasma membrane] (REACT_18484), G protein alpha:GDP complex [plasma membrane] (REACT_17462), Thrombin activated PAR:G12/13 (active) [plasma membrane] (REACT_17549), Thrombin-activated PAR:Gq (inactive) [plasma membrane] (REACT_17676), ADP:P2Y prurinoceptor 1:G-protein Gq (active) [plasma membrane] (REACT_20825), Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (active) [plasma membrane] (REACT_22976), Heterotrimeric G-protein Gz (active) [plasma membrane] (REACT_23379), G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (REACT_19870), G-protein alpha (q):GRK5 [plasma membrane] (REACT_19592), Thrombin-activated PAR:Gq (active) [plasma membrane] (REACT_17562), Gustducin Complex (alpha, beta, gamma subunits) [plasma membrane] (REACT_24604), Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (REACT_23143), G-protein alpha (q/11): GTP [plasma membrane] (REACT_5863), G13-activated p115-RhoGEF [plasma membrane] (REACT_3301), OR - G Protein Trimer Complex [plasma membrane] (REACT_17238), Heterotrimeric G-protein G13 (inactive) [plasma membrane] (REACT_17830), G-alpha(t)-GDP [plasma membrane] (REACT_18975), G alpha-olf:GDP complex [plasma membrane] (REACT_17352), G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (REACT_19687), p(S27)-G protein alpha (z):GTP [plasma membrane] (REACT_22530), G-protein alpha (13):GTP [plasma membrane] (REACT_18118), Heterotrimeric G-protein Gq (active) [plasma membrane] (REACT_5824), G-protein alpha (12/13):LARG:Plexin B1 [plasma membrane] (REACT_19937), Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (REACT_18059), Heterotrimeric G-protein [plasma membrane] (REACT_17846), TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (REACT_20823), G-protein alpha (12):GDP [plasma membrane] (REACT_2575), Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (REACT_22865), G(q) alpha: GDP Complex (pancreatic beta cell) [plasma membrane] (REACT_23125), Heterotrimeric G-protein Gz (inactive) [plasma membrane] (REACT_22728), Opioid:MOR:G protein-GDP complex [plasma membrane] (REACT_15815), Heterotrimeric G-protein G13 (active) [plasma membrane] (REACT_17395), G-protein alpha (z):GTP [plasma membrane] (REACT_20258), G-protein alpha (12/13):LARG [plasma membrane] (REACT_19624), G protein-GDP complex [plasma membrane] (REACT_15793), G(q):GDP: G beta: G gamma Complex (pancreatic beta cell) [plasma membrane] (REACT_18540), G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (REACT_18859), Opioid:MOR:G protein-GTP complex [plasma membrane] (REACT_15831), Heterotrimeric G-protein Gi (active) [plasma membrane] (REACT_20744), G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (REACT_15796), Heterotrimeric G-protein Gi (inactive) [plasma membrane] (REACT_20935), G-protein alpha i/o:GTP Complex [plasma membrane] (REACT_18504), (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (REACT_15853), G-protein alpha i/o:GDP Complex [plasma membrane] (REACT_18857), TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (REACT_20781), G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (REACT_17212).
REACTOME_PATHWAY: ADP signalling through P2Y purinoceptor 1 (REACT_19140), Thrombin signalling through proteinase activated receptors (PARs) (REACT_21384), Adenylate cyclase activating pathway (REACT_15312), ADP signalling through P2Y purinoceptor 12 (REACT_20653), G alpha (z) signalling events (REACT_91871), G alpha (12/13) signalling events (REACT_85741), G-protein mediated events (REACT_15526), G-protein mediated events (REACT_99045), Thromboxane signalling through TP receptor (REACT_20647), Inhibition of Insulin Secretion by Adrenaline/Noradrenaline (REACT_18339), Aquaporin-mediated transport (REACT_83369), G alpha (z) signalling events (REACT_19333), G-protein activation (REACT_15457), Transmembrane transport of small molecules (REACT_102897), PLC beta mediated events (REACT_80001), Hemostasis (REACT_92318), Diabetes pathways (REACT_15380), G alpha (i) signalling events (REACT_19231), Glucagon signaling in metabolic regulation (REACT_97918), Platelet homeostasis (REACT_81787), Signaling by GPCR (REACT_92902), Opioid Signalling (REACT_106208), Regulation of Water Balance by Renal Aquaporins (REACT_107038), Hemostasis (REACT_604), Adenylate cyclase inhibitory pathway (REACT_15333), G alpha (i) signalling events (REACT_82176), G alpha (z) signalling events (REACT_101356), G alpha (q) signalling events (REACT_18283), Transmission across Chemical Synapses (REACT_105301), Platelet Activation (REACT_88667), Aquaporin-mediated transport (REACT_32279), Adenylate cyclase activating pathway (REACT_99513), G alpha (q) signalling events (REACT_94531), G alpha (z) signalling events (REACT_29998), Inhibition of adenylate cyclase pathway (REACT_29125), Glucagon signaling in metabolic regulation (REACT_83177), Integration of energy metabolism (REACT_1505), Opioid Signalling (REACT_106868), Signal amplification (REACT_20524), Regulation of Insulin Secretion by Fatty Acids Bound to GPR40 (FFAR1) (REACT_19193), Adenylate cyclase activating pathway (REACT_79509), G alpha (s) signalling events (REACT_81642), Integration of energy metabolism (REACT_89538), Platelet activation triggers (REACT_622), Activation of GABAB receptors (REACT_25330), Formation of Platelet plug (REACT_104262), Opioid Signalling (REACT_15295), G-protein mediated events (REACT_81829), G alpha (s) signalling events (REACT_105431), GPCR downstream signaling (REACT_89233), Signaling by GPCR (REACT_81368), GPCR downstream signaling (REACT_19184), GABA B receptor activation (REACT_25031), Olfactory Signaling Pathway (REACT_15488), G-protein activation (REACT_85891), GABA receptor activation (REACT_25199), Regulation of Insulin Secretion by Free Fatty Acids (REACT_19375), Integration of energy metabolism (REACT_31409), G-protein activation (REACT_83156), Platelet activation triggers (REACT_78872), Transmembrane transport of small molecules (REACT_86409), Prostacyclin signalling through prostacyclin receptor (REACT_90454), GPCR downstream signaling (REACT_90453), Activation of GABAB receptors (REACT_87363), Formation of Platelet plug (REACT_20), Neuroransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell (REACT_15370), Signaling by GPCR (REACT_14797), Signal amplification (REACT_107520), PLC beta mediated events (REACT_30626), Signaling by GPCR (REACT_83331), PLC beta mediated events (REACT_15426), G alpha (q) signalling events (REACT_78862), Transmission across Chemical Synapses (REACT_13477), Regulation of Insulin Secretion by Acetylcholine (REACT_18405), G alpha (12/13) signalling events (REACT_18407), PKA activation in glucagon signalling (REACT_80338), G alpha (12/13) signalling events (REACT_107383), GABA B receptor activation (REACT_37805), Thromboxane signalling through TP receptor (REACT_32234), GPCR downstream signaling (REACT_81307), GABA receptor activation (REACT_32964), Synaptic Transmission (REACT_13685), PKA activation in glucagon signalling (REACT_109694), Neuroransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell (REACT_92810), Adenylate cyclase inhibitory pathway (REACT_104417), Platelet Activation (REACT_798), Opioid Signalling (REACT_32504), G alpha (i) signalling events (REACT_87312), Regulation of Water Balance by Renal Aquaporins (REACT_99705), Inhibition of adenylate cyclase pathway (REACT_25282), Regulation of Insulin Secretion (REACT_18325), G-protein activation (REACT_85866), Synaptic Transmission (REACT_29595).
These properties come from phylome analysis
molecular_function: GTP binding, signal transducer activity.
cellular_component: nucleus.
biological_process: regulation of root morphogenesis, root development, response to mannitol stimulus, response to fructose stimulus, response to glucose stimulus, response to sucrose stimulus, response to abscisic acid stimulus, response to ethylene stimulus, thigmotropism, gravitropism, G-protein coupled receptor protein signaling pathway.
These properties come from blast2go analysis
molecular_function: GTP binding, signal transducer activity.
biological_process: G-protein coupled receptor protein signaling pathway, signal transduction.
