Protein coding gene MELO3C013879
Accession: MELO3C013879
Name: MELO3C013879
Description: Similar to Regulator of nonsense transcripts 1 homolog (Arabidopsis thaliana) (uniprot_sprot:sp|Q9FJR0|RENT1_ARATH)
Properties
These properties come from blast2go analysis
molecular_function: zinc ion binding, ATP binding, protein binding, ATP-dependent RNA helicase activity, RNA binding, chromatin binding, DNA binding.
cellular_component: cytoplasm, chromatin.
biological_process: histone mRNA catabolic process, cell cycle, regulation of translational termination, mRNA export from nucleus, DNA repair, DNA replication, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
These properties come from reactome analysis
REACTOME_REACTION: Formation of UPF1:eRF3 Complex on mRNA with a Premature Termination Codon and No Exon Junction Complex (REACT_75917), UPF1 Binds an mRNP with a Termination Codon Preceding an Exon Junction Complex (REACT_75753), SMG1 Phosphorylates UPF1 (Enhanced by Exon Junction Complex) (REACT_75910).
biological_process: mRNA metabolic process, RNA metabolic process.
REACTOME_COMPLEX: mRNA Cleaved by SMG6 [cytosol] (REACT_76273), SMG1:UPF1:EJC:Translated mRNP [cytosol] (REACT_76647), SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (REACT_76156), Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (REACT_76275), UPF1:eRF3 Complex on Translated mRNA [cytosol] (REACT_76212).
REACTOME_PATHWAY: Nonsense Mediated Decay Independent of the Exon Junction Complex (REACT_75768), Metabolism of RNA (REACT_21257), Nonsense-Mediated Decay (REACT_75886), Metabolism of mRNA (REACT_20605), Nonsense Mediated Decay Enhanced by the Exon Junction Complex (REACT_75822).
These properties come from phylome analysis
molecular_function: protein phosphatase 2A binding, helicase activity, zinc ion binding, ATP binding, protein binding, ATP-dependent RNA helicase activity, DNA binding.
cellular_component: plasma membrane, polysome, nucleus, cytoplasm.
biological_process: cellular response to hypoxia, nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, hermaphrodite genitalia development, embryonic genitalia morphogenesis, chromatin silencing at silent mating-type cassette, protein ubiquitination, RNA interference, sugar mediated signaling pathway, response to sucrose stimulus, intracellular mRNA localization, regulation of translational termination, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
These properties come from kegg analysis
KEGG_ORTHOLOGS: regulator of nonsense transcripts 1 [EC:3.6.4.-] (K14326).
COG: Superfamily I DNA and RNA helicases and helicase subunits (COG1112).
