Polypeptide MELO3C016952P1

Accession: MELO3C016952P1

Name: MELO3C016952P1

Description: Similar to Eukaryotic initiation factor iso-4F subunit p82-34 (Triticum aestivum PE=1 SV=2) (uniprot_sprot:sp|Q03387|IF41_WHEAT)

Sequence:

>MELO3C016952P1 Similar to Eukaryotic initiation factor iso-4F subunit p82-34 (Triticum aestivum PE=1 SV=2) (uniprot_sprot:sp|Q03387|IF41_WHEAT)
MQADQTVISLRPGGGGGLRGSRFVTPRFDSSSADSSSLRPHGGVASILKTGDLRFEGRERIQYTRDQLLQLREVATVPED
ILKVKLEVESEIGGEDQTWNRAESNPQPQSQSRYFEPDSRDWRGRSGQVPGSTEEGPWDANKDMSGQSESRFQDSNNRIQ
VSGNQGVGTPALIKAEVPWSVRRGNISEKERVLKTVKGILNKLTPEKFDLLKGQLIDSGITSADILKDVISLIFEKAVFE
PTFCPMYALLCSDLNEKLPSFASDVPGEKDITFKRVLLNICQEAFEGADNLRAEIRQMTSPEQEMERRDKERMVKLRTLG
NIRLIGELLKQKMVPEKIVHHIVLELLGPDPKTCPAEENVEAISQFFNTIGKQLDESPKSRRVNDLYFSRLKELTVNTQL
APRLRFMVRDVLDLRANNWVPRREEVKAKTITEIHTEAEKNLGLRPGSVAMMRNGRNAEALGGLSPGGFPVARPGFGGMM
PGMPGARKMPGMPGLESDNWEVPRSRSMPRGESGGHAQASARVQSSLMGKTPSISSKYLPQGSGGVITGKTSALLQGSAA
TSPARPPSSMPVALNPKPVAPVAPVVSSPQKPAVPATSNLADLQKKTVSLLEEYFSVRILDEALQCVEELKSSAYHPEVV
KKSLTMALEKIPPRVDPVVKLLEHLLCKNVLTAKDIGTGCYLYGSQMDDIGIDLPKAPNNFGEILGMLILIGGLDFTVVK
EILEKLEDNYFQKSIFDGAMKTLKSSPSGERILATQSVEVQACETLLA*

Download fasta sequence.

Properties

These properties come from reactome analysis


REACTOME_REACTION: Formation of UPF1:eRF3 Complex on mRNA with a Premature Termination Codon and No Exon Junction Complex (REACT_75917), Ribosomal scanning (REACT_1516), Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a closed-loop conformation (REACT_1515), SMG1 Phosphorylates UPF1 (Enhanced by Exon Junction Complex) (REACT_75910), Formation of the cap-binding eIF4F complex (REACT_441), Deadenylation of mRNA by PARN (REACT_20662), UPF1 Binds an mRNP with a Termination Codon Preceding an Exon Junction Complex (REACT_75753), Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (REACT_1595), Association of AUF1 with Translation and Heat Shock Proteins (REACT_25267), Deadenylation of mRNA by the CCR4-NOT Complex (REACT_20651), Start codon recognition (REACT_656), Formation of translation initiation complexes containing mRNA that does not circularize (REACT_1904), eIF4F binds to mRNP (REACT_918), Partial Deadenylation of mRNA by the PAN2-PAN3 Complex (REACT_20606), Phosphorylation and activation of eIF4G by activated S6K1 (REACT_6870), eIF2:GTP is hydrolyzed, eIFs are released (REACT_1060).

biological_process: translation, mRNA metabolic process, insulin receptor signaling pathway, gene expression, nuclear-transcribed mRNA poly(A) tail shortening, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, cellular protein metabolic process, RNA metabolic process.

REACTOME_COMPLEX: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] (REACT_2288), SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (REACT_76156), AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (REACT_25605), eIF4F [cytosol] (REACT_4441), mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (REACT_76207), 43S:mRNA:eIF4F:eIF4B:eIF4H [cytosol] (REACT_4439), 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (REACT_3267), Partially Deadenylated mRNA Complex [cytosol] (REACT_20682), UPF1:eRF3 Complex on Translated mRNA [cytosol] (REACT_76212), Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (REACT_76767), SMG1:UPF1:EJC:Translated mRNP [cytosol] (REACT_76647), Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (REACT_76510), mRNA Cleaved by SMG6 [cytosol] (REACT_76273), eIF4F:mRNP [cytosol] (REACT_4731), Translatable mRNA Complex [cytosol] (REACT_21129), mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (REACT_76342), Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (REACT_76275), 48S complex [cytosol] (REACT_5152), phospho-L13a associated wth the 3 UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (REACT_5151), mRNA:eIF4F:eIF4B:eIF4H [cytosol] (REACT_2596).

REACTOME_PATHWAY: PI3K Cascade (REACT_976), Translation initiation complex formation (REACT_1979), Regulation of mRNA Stability by Proteins that Bind AU-rich Elements (REACT_24994), Nonsense Mediated Decay Independent of the Exon Junction Complex (REACT_75768), Nonsense-Mediated Decay (REACT_75886), IRS-related events (REACT_762), IRS-mediated signalling (REACT_332), Translation (REACT_1014), Nonsense Mediated Decay Enhanced by the Exon Junction Complex (REACT_75822), mTOR signalling (REACT_6838), mTORC1-mediated signalling (REACT_6964), S6K1-mediated signalling (REACT_6754), 3 -UTR-mediated translational regulation (REACT_1762), Cap-dependent Translation Initiation (REACT_2099), S6K1 signalling (REACT_6772), Gene Expression (REACT_71), Deadenylation of mRNA (REACT_20514), L13a-mediated translational silencing of Ceruloplasmin expression (REACT_79), Destabilization of mRNA by AUF1 (hnRNP D0) (REACT_25325), Signaling by Insulin receptor (REACT_498), Eukaryotic Translation Initiation (REACT_2159), Metabolism of mRNA (REACT_20605), Insulin receptor signalling cascade (REACT_1195), PKB-mediated events (REACT_456), GTP hydrolysis and joining of the 60S ribosomal subunit (REACT_2085), Metabolism of RNA (REACT_21257), Metabolism of proteins (REACT_17015), Deadenylation-dependent mRNA decay (REACT_20639), Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (REACT_1258), Ribosomal scanning and start codon recognition (REACT_931).

These properties come from phylome analysis


molecular_function: binding, protein binding.

biological_process: RNA metabolic process.

These properties come from blast2go analysis


molecular_function: protein binding, translation initiation factor activity.

cellular_component: eukaryotic translation initiation factor 4F complex, plastid.

biological_process: spread of virus in host, cell to cell, RNA metabolic process, response to virus.

Locations

Located in CM3.5_scaffold00029 from 3351661 to 3356475.

This polypeptide in other databases

In PhylomeDB is Phy003A6CS_CUCME .

Related features