Protein coding gene MELO3C019700
Accession: MELO3C019700
Name: MELO3C019700
Description: Similar to DNA-directed RNA polymerases I, II, and III subunit RPABC1 (Caenorhabditis briggsae) (uniprot_sprot:sp|A8XGH1|RPAB1_CAEBR)
Properties
These properties come from blast2go analysis
molecular_function: DNA binding, DNA-directed RNA polymerase activity, protein binding.
cellular_component: nucleus.
biological_process: transcription, DNA-dependent.
These properties come from reactome analysis
REACTOME_PATHWAY: RNA Polymerase II Transcription (REACT_99228), Dual incision reaction in TC-NER (REACT_109190), RNA Polymerase III Transcription Initiation (REACT_89165), RNA Polymerase III Transcription Initiation (REACT_33287), RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (REACT_106372), mRNA Splicing (REACT_94469), Formation of the Early Elongation Complex (REACT_101279), mRNA Capping (REACT_102770), RNA Polymerase III Transcription (REACT_84770), RNA Polymerase III Transcription Initiation From Type 1 Promoter (REACT_101904), RNA Polymerase III Transcription (REACT_91182), mRNA Splicing - Major Pathway (REACT_91611), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_1655), Elongation arrest and recovery (REACT_1892), RNA Polymerase III Transcription Initiation From Type 1 Promoter (REACT_109979), Tat-mediated elongation of the HIV-1 transcript (REACT_6162), Formation of transcription-coupled NER (TC-NER) repair complex (REACT_1941), RNA Polymerase III Transcription Initiation From Type 2 Promoter (REACT_85004), RNA Polymerase II Promoter Escape (REACT_32829), Pausing and recovery of Tat-mediated HIV-1 elongation (REACT_6143), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_34355), RNA Pol II CTD phosphorylation and interaction with CE (REACT_90040), Abortive elongation of HIV-1 transcript in the absence of Tat (REACT_6261), mRNA Capping (REACT_85081), RNA Polymerase II HIV-1 Promoter Escape (REACT_6253), Formation of the Early Elongation Complex (REACT_846), HIV Life Cycle (REACT_6256), HIV-1 elongation arrest and recovery (REACT_6259), Formation of HIV-1 elongation complex in the absence of HIV-1 Tat (REACT_22201), Transcription-coupled NER (TC-NER) (REACT_29182), RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (REACT_102763), Transcription (REACT_87991), RNA Polymerase III Transcription Termination (REACT_84701), Transcription (REACT_1788), mRNA Capping (REACT_1470), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_98915), RNA Polymerase III Transcription Initiation From Type 2 Promoter (REACT_95797), RNA Pol II CTD phosphorylation and interaction with CE (REACT_30624), Transcription-coupled NER (TC-NER) (REACT_87141), mRNA Splicing - Minor Pathway (REACT_101749), RNA Polymerase II Pre-transcription Events (REACT_82727), RNA Polymerase III Transcription Termination (REACT_79014), Formation of the HIV-1 Early Elongation Complex (REACT_6319), Pausing and recovery of HIV-1 elongation (REACT_6244), RNA Polymerase III Abortive And Retractive Initiation (REACT_99565), RNA Polymerase II Promoter Escape (REACT_81662), Gene Expression (REACT_91657), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_109232), RNA Polymerase III Transcription (REACT_1371), mRNA Splicing - Major Pathway (REACT_93740), mRNA Splicing (REACT_107931), RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (REACT_21352), DNA Repair (REACT_88201), Transcription (REACT_93622), RNA Pol II CTD phosphorylation and interaction with CE (REACT_33716), mRNA Capping (REACT_93735), RNA Polymerase II Transcription Elongation (REACT_81750), RNA Polymerase II Promoter Escape (REACT_107789), RNA Polymerase II Transcription (REACT_97471), Processing of Capped Intron-Containing Pre-mRNA (REACT_109442), mRNA Processing (REACT_109337), RNA Polymerase III Chain Elongation (REACT_33917), RNA Polymerase II Transcription (REACT_1366), Elongation arrest and recovery (REACT_91132), RNA Polymerase II Pre-transcription Events (REACT_91707), Formation and Maturation of mRNA Transcript (REACT_77979), Formation and Maturation of mRNA Transcript (REACT_92291), RNA Polymerase III Transcription Initiation From Type 1 Promoter (REACT_347), DNA Repair (REACT_91442), mRNA Processing (REACT_1675), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_85257), Formation of RNA Pol II elongation complex (REACT_1845), mRNA Splicing (REACT_98879), RNA Polymerase III Transcription Initiation (REACT_102986), Transcription of the HIV genome (REACT_6233), mRNA Capping (REACT_85562), RNA Pol II CTD phosphorylation and interaction with CE (REACT_6237), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_87559), HIV-1 Transcription Initiation (REACT_6332), RNA Pol II CTD phosphorylation and interaction with CE (REACT_975), RNA Polymerase III Chain Elongation (REACT_83012), Formation of transcription-coupled NER (TC-NER) repair complex (REACT_86892), RNA Polymerase III Transcription Termination (REACT_86112), RNA Polymerase III Abortive And Retractive Initiation (REACT_78758), RNA Polymerase III Transcription Initiation From Type 3 Promoter (REACT_33164), mRNA Processing (REACT_80866), Formation and Maturation of mRNA Transcript (REACT_32779), Formation of the Early Elongation Complex (REACT_97522), DNA Repair (REACT_216), RNA Polymerase II Promoter Escape (REACT_2089), RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (REACT_33462), mRNA Splicing - Minor Pathway (REACT_1753), HIV Infection (REACT_6185), RNA Polymerase II Transcription Initiation (REACT_1851), Gene Expression (REACT_108313), RNA Polymerase II Pre-transcription Events (REACT_22107), Transcription (REACT_34268), RNA Polymerase III Chain Elongation (REACT_756), RNA Polymerase III Transcription Initiation (REACT_94057), Tat-mediated HIV-1 elongation arrest and recovery (REACT_6344), Nucleotide Excision Repair (REACT_106982), Formation of HIV-1 elongation complex containing HIV-1 Tat (REACT_6346), Processing of Capped Intron-Containing Pre-mRNA (REACT_30593), RNA Polymerase II Transcription Initiation (REACT_88340), RNA Polymerase III Abortive And Retractive Initiation (REACT_33938), RNA Polymerase II Transcription Elongation (REACT_107633), Elongation arrest and recovery (REACT_79615), mRNA Splicing (REACT_1735), Transcription-coupled NER (TC-NER) (REACT_29721), Formation of transcription-coupled NER (TC-NER) repair complex (REACT_102536), Gene Expression (REACT_71), Pausing and recovery of elongation (REACT_83577), Dual incision reaction in TC-NER (REACT_81556), RNA Polymerase III Chain Elongation (REACT_78831), mRNA Splicing - Minor Pathway (REACT_101135), RNA Polymerase III Chain Elongation (REACT_104942), Transcription (REACT_100899), RNA Polymerase II Pre-transcription Events (REACT_99660), Pausing and recovery of elongation (REACT_769), Processing of Capped Intron-Containing Pre-mRNA (REACT_29012), Gene Expression (REACT_98256), RNA Polymerase III Transcription Initiation (REACT_281), RNA Pol II CTD phosphorylation and interaction with CE (REACT_28314), mRNA Processing (REACT_29019), RNA Polymerase II Transcription (REACT_99950), RNA Polymerase III Transcription Termination (REACT_104517), Nucleotide Excision Repair (REACT_88933), Nucleotide Excision Repair (REACT_1826), Nucleotide Excision Repair (REACT_84438), DNA Repair (REACT_107446), RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (REACT_106642), Late Phase of HIV Life Cycle (REACT_6361), RNA Polymerase III Abortive And Retractive Initiation (REACT_22339), RNA Polymerase III Transcription Initiation From Type 2 Promoter (REACT_1036), RNA Polymerase III Transcription Termination (REACT_63), Gene Expression (REACT_105649), RNA Polymerase II Transcription Elongation (REACT_92836), Processing of Capped Intron-Containing Pre-mRNA (REACT_82582), Formation of transcription-coupled NER (TC-NER) repair complex (REACT_91566), DNA Repair (REACT_93704), Formation of the Early Elongation Complex (REACT_99528), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_34737), Dual incision reaction in TC-NER (REACT_2222), Transcription-coupled NER (TC-NER) (REACT_1628), RNA Polymerase III Transcription Initiation From Type 2 Promoter (REACT_97189), RNA Polymerase II Pre-transcription Events (REACT_82104), Processing of Capped Intron-Containing Pre-mRNA (REACT_125), RNA Polymerase II Transcription Initiation (REACT_87429), Formation of the Early Elongation Complex (REACT_29380), Formation and Maturation of mRNA Transcript (REACT_2039), RNA Polymerase II Transcription (REACT_106213), RNA Polymerase II Transcription Elongation (REACT_87946), RNA Polymerase II Promoter Escape (REACT_109274), RNA Polymerase III Transcription (REACT_79230), RNA Polymerase III Transcription Initiation From Type 3 Promoter (REACT_571), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_79444), RNA Polymerase II Transcription Elongation (REACT_833), RNA Polymerase III Transcription (REACT_107815), RNA Polymerase II Transcription Initiation (REACT_104036), Dual incision reaction in TC-NER (REACT_30923), RNA Polymerase II Transcription Initiation (REACT_104646), Nucleotide Excision Repair (REACT_96106), mRNA Processing (REACT_90209), mRNA Splicing - Major Pathway (REACT_467), Pausing and recovery of elongation (REACT_111024), RNA Polymerase III Abortive And Retractive Initiation (REACT_90206), Formation and Maturation of mRNA Transcript (REACT_96378), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_83749), Dual incision reaction in TC-NER (REACT_94657), mRNA Splicing - Minor Pathway (REACT_91088), RNA Polymerase III Transcription Initiation From Type 2 Promoter (REACT_90709), Formation of transcription-coupled NER (TC-NER) repair complex (REACT_83742), Transcription-coupled NER (TC-NER) (REACT_96116), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_834), HIV-1 Transcription Elongation (REACT_6274).
REACTOME_REACTION: RNA Polymerase II Promoter Opening: First Transition (REACT_29850), RNA Polymerase III Abortive Initiation At Type 2 Open Promoters (REACT_30852), Phosphorylation (Ser5) of RNA pol II CTD (REACT_31984), Pol II elongation complex moves on the template as transcript elongates (REACT_30284), Formation of AT-AC B Complex (REACT_1253), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_1251), Formation of the Spliceosomal B Complex (REACT_48), RNA Polymerase II Promoter Opening: First Transition (REACT_80107), Abortive Initiation After Second Transition (REACT_1793), Abortive initiation after formation of the first phosphodiester bond (REACT_32630), Internal Methylation of mRNA (REACT_30916), Formation of the closed pre-initiation complex (REACT_82855), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_1467), Abortive HIV-1 Initiation Before Second Transition (REACT_6203), RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters (REACT_251), RNA Polymerase III Promoter Opening at Type 1 Promoters (REACT_796), Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (REACT_254), Internal Methylation of mRNA (REACT_1720), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_1082), Phosphorylation (Ser5) of RNA pol II CTD (REACT_90675), Pol II elongation complex moves on the template as transcript elongates (REACT_2053), RNA Polymerase III Termination and release of transcribed mRNA (REACT_30092), Abortive initiation after formation of the first phosphodiester bond (REACT_653), Fall Back to Closed Pre-initiation Complex (REACT_6211), ATAC spliceosome mediated 3 splice site cleavage, exon ligation (REACT_1494), Abortive termination of HIV-1 elongation after arrest (Tat-containing elongation complex) (REACT_6269), Resumption of transcription after TC-NER (REACT_551), Activation of GT (REACT_103913), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_79829), Abortive HIV-1 Initiation After Second Transition (REACT_6265), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_2233), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_95548), Extrusion of 5-end of 30 nt long HIV-1 transcript through the pore in Pol II complex (REACT_6148), TFIIS-mediated recovery of HIV-1 elongation from arrest (REACT_6252), RNA Polymerase III Abortive Initiation At Type 2 Open Promoters (REACT_1061), DSIF complex binds to RNA Pol II (hypophosphorylated) (REACT_6250), Formation of the closed pre-initiation complex (REACT_91116), 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest (REACT_6254), RNA Polymerase II Promoter Opening: First Transition (REACT_94679), RNA Polymerase III Termination and release of transcribed mRNA (REACT_1301), RNA Polymerase III Productive Transcription (REACT_89159), Fall Back to Closed Pre-initiation Complex (REACT_98220), Formation of the CE:GMP intermediate complex (REACT_90910), Methylation of GMP-cap by RNA Methyltransferase (REACT_97945), RNA Polymerase III Promoter Opening at Type 2 Promoters (REACT_103737), Abortive Initiation Before Second Transition (REACT_106763), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_83079), Resumption of RNA Polymerase III Productive Transcription (REACT_109350), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_102473), DSIF complex binds to RNA Pol II (hypophosphorylated) (REACT_802), NTP Binds Active Site of RNA Polymerase II (REACT_84849), Methylation of GMP-cap by RNA Methyltransferase (REACT_404), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_29457), Formation of active Pol II complex with lesioned DNA template (REACT_96240), Formation of active Pol II complex with lesioned DNA template (REACT_28257), Formation of active Pol II complex with lesioned DNA template (REACT_105740), TFIIS-mediated recovery of elongation from arrest (REACT_1094), RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters (REACT_109747), Resumption of elongation after recovery from pausing (REACT_99936), Formation of AT-AC C complex (REACT_83124), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_1968), Separation of abortive HIV-1 transcript from template (REACT_6159), Pol II elongation complex moves on the HIV-1 template as transcript elongates (REACT_6158), Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex (REACT_6311), Capping complex formation (REACT_32400), Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (REACT_34724), Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex (REACT_6316), Dissociation of transcript with 5-GMP from GT (REACT_30543), Resumption of RNA Polymerase III Productive Transcription (REACT_96798), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_95240), Binding of TFIIE to the growing preinitiation complex (REACT_82447), Resumption of elongation of HIV-1 transcript after recovery from pausing (REACT_6155), Resumption of elongation after recovery from pausing (REACT_79713), Formation of the closed pre-initiation complex (REACT_83351), Pol II elongation complex moves on the template as transcript elongates (REACT_30038), Addition of nucleotides between position +11 and +30 on HIV-1 transcript (REACT_6240), Dissociation of transcript with 5-GMP from GT (REACT_101219), Resumption of RNA Polymerase III Productive Transcription (REACT_1374), RNA Polymerase III Termination and release of transcribed mRNA (REACT_878), Addition of nucleotides leads to transcript elongation (REACT_107064), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_97660), Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (REACT_1779), Resumption of transcription after TC-NER (REACT_29828), NTP Binds Active Site of RNA Polymerase II (REACT_86985), RNA Polymerase III Abortive Initiation At Type 1 Open Promoters (REACT_31708), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_81068), Resumption of transcription after TC-NER (REACT_101665), Internal Methylation of mRNA (REACT_28726), RNA Polymerase III Termination and release of transcribed mRNA (REACT_95372), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_1567), 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (REACT_234), Displacement of stalled Pol II from the lesion site (REACT_82387), RNA Polymerase III Promoter Opening at Type 2 Promoters (REACT_81290), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_86649), Initiation of RNA Polymerase III Productive Transcription (REACT_99492), Formation of pre-mRNPs (REACT_1877), Fall Back to Closed Pre-initiation Complex (REACT_1702), Addition of nucleotides between position +11 and +30 (REACT_77879), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_78922), Dissociation of transcript with 5-GMP from GT (REACT_106203), Fall Back to Closed Pre-initiation Complex (REACT_92728), Initiation of RNA Polymerase III Productive Transcription (REACT_109134), TFIIS-mediated recovery of elongation from arrest (REACT_101748), Formation of the closed pre-initiation complex (REACT_632), RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters (REACT_2178), RNA Polymerase III Promoter Opening (REACT_1202), Addition of Nucleotides 5 through 9 on the growing Transcript (REACT_100344), ATAC spliceosome mediated 3 splice site cleavage, exon ligation (REACT_81825), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_1368), Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (REACT_1684), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_33423), RNA Polymerase III Initiation At a Simple Start Sequence (REACT_1686), Formation of the CE:GMP intermediate complex (REACT_1580), Dissociation of transcript with 5-GMP from GT (REACT_90647), RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters (REACT_2210), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_33504), Addition of nucleotides between position +11 and +30 (REACT_29713), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_28433), DSIF complex binds to RNA Pol II (hypophosphorylated) (REACT_110194), Addition of Nucleotides 5 through 9 on the growing Transcript (REACT_581), Formation of AT-AC C complex (REACT_110048), Capping complex formation (REACT_85029), RNA Polymerase III Productive Transcription (REACT_2251), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_108808), Formation of the Spliceosomal E complex (REACT_222), RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites (REACT_103091), Displacement of stalled Pol II from the lesion site (REACT_1284), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_423), ATAC spliceosome mediated Lariat formation,5 splice site cleavage (REACT_81731), RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites (REACT_170), RNA Polymerase III Transcriptional Pause at Terminator Sequence (REACT_84752), Initiation of RNA Polymerase III Productive Transcription (REACT_1179), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_28192), Formation of active Pol II complex with lesioned DNA template (REACT_97303), DSIF complex binds to RNA Pol II (hypophosphorylated) (REACT_32792), RNA Polymerase II Promoter Opening: First Transition (REACT_1844), RNA Polymerase III Promoter Opening at Type 2 Promoters (REACT_793), RNA Polymerase III Transcriptional Pause at Terminator Sequence (REACT_82930), RNA Pol II is blocked by the lesion leading to reduced transcription (REACT_101583), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_77594), RNA Polymerase III Abortive Initiation At Type 2 Open Promoters (REACT_106447), RNA Pol II is blocked by the lesion leading to reduced transcription (REACT_1947), Abortive Initiation After Second Transition (REACT_108713), Phosphorylation (Ser5) of RNA pol II CTD (REACT_6234), RNA Polymerase III Transcriptional Pause at Terminator Sequence (REACT_2064), Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (REACT_2066), DSIF complex binds to RNA Pol II (hypophosphorylated) (REACT_93493), Formation of an intermediate Spliceosomal C complex (REACT_625), Newly formed phosphodiester bond stabilized and PPi released (REACT_6333), HIV-1 Promoter Opening: First Transition (REACT_6134), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_102861), Abortive termination of elongation after arrest (REACT_95584), RNA Polymerase II Promoter Opening: First Transition (REACT_89694), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_86293), RNA Polymerase III Promoter Opening at Type 1 Promoters (REACT_109934), Beginning of RNA Polymerase III Productive Transcription (REACT_1217), NTP Binds Active Site of RNA Polymerase II (REACT_80520), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_103086), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_1055), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_88439), Activation of GT (REACT_893), RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites (REACT_2248), Internal Methylation of mRNA (REACT_85125), Formation of AT-AC B Complex (REACT_93825), Capping complex formation (REACT_86608), ATAC spliceosome mediated Lariat formation,5 splice site cleavage (REACT_2241), Formation of AT-AC B Complex (REACT_100957), RNA Polymerase III Promoter Opening at Type 2 Promoters (REACT_109940), Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (REACT_108403), Displacement of stalled Pol II from the lesion site (REACT_87615), NTP Binds Active Site of RNA Polymerase II (REACT_106132), RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites (REACT_110354), Addition of nucleotides between position +11 and +30 (REACT_28303), DSIF complex binds to RNA Pol II (hypophosphorylated) (REACT_93340), Formation of active Pol II complex with lesioned DNA template (REACT_1453), Fall Back to Closed Pre-initiation Complex (REACT_31744), RNA Polymerase III Transcriptional Pause at Terminator Sequence (REACT_31153), NTP Binds Active Site of RNA Polymerase II (REACT_1160), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_109877), Addition of nucleotides leads to transcript elongation (REACT_751), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_6220), NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex (REACT_6349), ATAC spliceosome mediated 3 splice site cleavage, exon ligation (REACT_77961), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_88546), Formation of AT-AC A complex (REACT_864), 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing (REACT_6347), Recruitment of elongation factors to form elongation complex (REACT_949), Lariat Formation and 5-Splice Site Cleavage (REACT_82009), Abortive HIV-1 initiation after formation of the first phosphodiester bond (REACT_6226), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_87062), ATAC spliceosome mediated 3 splice site cleavage, exon ligation (REACT_34550), Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (REACT_93916), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_77279), Resumption of transcription after TC-NER (REACT_80496), Methylation of GMP-cap by RNA Methyltransferase (REACT_34170), Phosphorylation (Ser5) of RNA pol II CTD (REACT_1185), Resumption of elongation of HIV-1 transcript after recovery from pausing (REACT_6299), ATAC spliceosome mediated Lariat formation,5 splice site cleavage (REACT_81096), Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (REACT_6297), Formation of DSIF:NELF:early elongation complex (REACT_96991), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_6295), RNA Polymerase III Abortive Initiation At Type 2 Open Promoters (REACT_90817), Formation of the active Spliceosomal C complex (REACT_89446), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_86674), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_79518), Recognition and binding of the mRNA cap by the cap-binding complex (REACT_687), Addition of nucleotides between position +11 and +30 (REACT_209), RNA Polymerase III Productive Transcription (REACT_93859), Activation of GT (REACT_84234), Resumption of transcription after TC-NER (REACT_88101), Limited elongation of the HIV-1 transcript (REACT_6192), RNA Polymerase III Abortive Initiation At Type 3 Open Promoters (REACT_1616), Formation of AT-AC C complex (REACT_1615), Lariat Formation and 5-Splice Site Cleavage (REACT_1935), Abortive termination of early transcription elongation by DSIF:NELF (REACT_89590), Binding of TFIIE to the growing preinitiation complex (REACT_78942), Binding of TFIIE to the growing preinitiation complex (REACT_32367), RNA Pol II is blocked by the lesion leading to reduced transcription (REACT_90318), Formation of AT-AC B Complex (REACT_101559), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_85239), Formation of the Spliceosomal B Complex (REACT_90182), 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing (REACT_6214), Assembly of repair proteins at the site of Pol II blockage (REACT_1584), RNA Pol II is blocked by the lesion leading to reduced transcription (REACT_86848), Binding of TFIIE to the growing preinitiation complex (REACT_1821), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_29917), Recruitment of elongation factors to form HIV-1 elongation complex (REACT_6358), Formation of DSIF:NELF:HIV-1 early elongation complex (REACT_6357), ATAC spliceosome mediated Lariat formation,5 splice site cleavage (REACT_29379), Abortive termination of elongation after arrest (REACT_6355), RNA Polymerase III Abortive Initiation (REACT_616), Abortive termination of HIV-1 elongation after arrest (REACT_6352), Abortive Initiation After Second Transition (REACT_103184), Cleavage at the 3-Splice Site and Exon Ligation (REACT_1331), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_108201), Abortive Initiation After Second Transition (REACT_103180), RNA Polymerase III Transcriptional Pause at Terminator Sequence (REACT_473), Initiation of RNA Polymerase III Productive Transcription (REACT_90945), Addition of nucleotides leads to transcript elongation (REACT_100466), TFIIS-mediated recovery of elongation from arrest (REACT_102520), RNA Polymerase III Termination and release of transcribed mRNA (REACT_76992), Separation of elongating transcript from template (REACT_81515), RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters (REACT_106571), Capping complex formation (REACT_2186), Formation of Exon Junction Complex (REACT_85923), Formation of the active Spliceosomal C complex (REACT_63591), Nucleophillic attack by 3-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (REACT_6285), Formation of the CE:GMP intermediate complex (REACT_92552), Elongating transcript encounters a lesion in the template (REACT_1138), Formation of the CE:GMP intermediate complex (REACT_79193), Formation of an intermediate Spliceosomal C complex (REACT_91565), Abortive termination of early transcription elongation by DSIF:NELF (REACT_86233), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_96127), Activation of GT (REACT_96305), RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters (REACT_106059), Activation of GT (REACT_6298), Formation of an intermediate Spliceosomal C complex (REACT_108009), Abortive termination of early transcription elongation by DSIF:NELF (REACT_87802), Abortive termination of elongation after arrest (REACT_98053), Displacement of stalled Pol II from the lesion site (REACT_28718), RNA Polymerase III Productive Transcription (REACT_98770), Formation of Exon Junction Complex (REACT_774), Displacement of stalled Pol II from the lesion site (REACT_108076), Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition (REACT_6208), Formation of Exon Junction Complex (REACT_92827), Phosphorylation (Ser5) of RNA pol II CTD (REACT_77857), Recognition and binding of the HIV-1 mRNA cap by the cap-binding complex (REACT_6166), Phosphorylation (Ser5) of RNA pol II CTD (REACT_91157), Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (REACT_82574), Formation of the closed pre-initiation complex (REACT_98407), Separation of elongating transcript from template (REACT_2030), Separation of elongating HIV-1 transcript from template (REACT_6204), 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (REACT_83561), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_6206), Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (REACT_110236), Abortive termination of HIV-1 early transcription elongation by DSIF:NELF (REACT_6281), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_105022), Formation of the Spliceosomal B Complex (REACT_109266), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_30335), RNA Pol II is blocked by the lesion leading to reduced transcription (REACT_34608), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_103987), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_100578), RNA Polymerase III Abortive Initiation At Type 1 Open Promoters (REACT_1241), Methylation of GMP-cap by RNA Methyltransferase (REACT_93915), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_88577), Abortive termination of early transcription elongation by DSIF:NELF (REACT_989), Activation of GT (REACT_106797), Formation of the active Spliceosomal C complex (REACT_1554), Formation of AT-AC C complex (REACT_95722), TFIIS-mediated recovery of elongation from arrest (REACT_6330), Formation of DSIF:NELF:early elongation complex (REACT_981), Capping complex formation (REACT_91663), Resumption of RNA Polymerase III Productive Transcription (REACT_93305), 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (REACT_1645), Formation of the CE:GMP intermediate complex (REACT_101635), Lariat Formation and 5-Splice Site Cleavage (REACT_28087), Resumption of elongation after recovery from pausing (REACT_1638), RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites (REACT_80924), RNA Polymerase III Promoter Opening at Type 3 Promoters (REACT_1485), Fall Back to Closed Pre-initiation Complex (REACT_100253), Separation of elongating transcript from template (REACT_34213), Formation of the Spliceosomal A Complex (REACT_788), Addition of nucleotides between position +11 and +30 (REACT_90076), Addition of nucleotides 5 through 9 on the growing HIV-1 transcript (REACT_6172), Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex (REACT_6170), Addition of nucleotides leads to HIV-1 transcript elongation (REACT_6278), 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest (REACT_6174), RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters (REACT_103226), Recruitment of elongation factors to form HIV-1 elongation complex (REACT_6275), Abortive Initiation Before Second Transition (REACT_543), Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (REACT_704), Dissociation of transcript with 5-GMP from GT (REACT_703), 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (REACT_30549).
REACTOME_COMPLEX: HIV-1 Tat-containing paused processive elongation complex [nucleoplasm] (REACT_6389), RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (REACT_2692), Capping complex (intermediate) [nucleoplasm] (REACT_3580), Pol II Promoter Escape Complex [nucleoplasm] (REACT_3851), Capping complex (hydrolyzed) [nucleoplasm] (REACT_4969), HIV-1 transcription complex containing 11 nucleotide long transcript [nucleoplasm] (REACT_6664), Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (REACT_2595), RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (REACT_3171), RNA Polymerase III Open SUP4 tRNATyr Promoter Complex [nucleoplasm] (REACT_4509), HIV-1 closed pre-initiation complex [nucleoplasm] (REACT_6553), RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (REACT_4889), Stalled Pol II complex with damaged DNA hybrid [nucleoplasm] (REACT_3072), Arrested processive elongation complex [nucleoplasm] (REACT_4675), Spliceosomal Intermediate C Complex [nucleoplasm] (REACT_5473), RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (REACT_6382), pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (REACT_3183), RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (REACT_6521), HIV-1 Promoter Escape Complex [nucleoplasm] (REACT_6417), RNA Polymerase III Holoenzyme [nucleoplasm] (REACT_4184), RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (REACT_6659), Spliceosomal Active C Complex [nucleoplasm] (REACT_2680), Aborted elongation complex after arrest [nucleoplasm] (REACT_6654), RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (REACT_4217), RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (REACT_2371), Spliceosomal A Complex [nucleoplasm] (REACT_4512), Paused RNA Polymerase III Transcription Complex [nucleoplasm] (REACT_5042), CE:Pol II CTD:Spt5 complex [nucleoplasm] (REACT_6491), RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex [nucleoplasm] (REACT_2997), Spliceosomal B Complex [nucleoplasm] (REACT_3078), Capping complex (with freed 5- GMP) [nucleoplasm] (REACT_4741), Elongation complex prior to separation [nucleoplasm] (REACT_5853), HIV-1 Tat-containing arrested processive elongation complex [nucleoplasm] (REACT_6532), Tat-containing early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (REACT_6536), Elongation complex with separated and uncleaved transcript [nucleoplasm] (REACT_5512), DSIF:NELF:early elongation complex after limited nucleotide addition [nucleoplasm] (REACT_6432), HIV-1 transcription complex [nucleoplasm] (REACT_6433), RNA Polymerase III SUP4 tRNATyr gene Transcription Complex [nucleoplasm] (REACT_2261), pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (REACT_5212), Processive elongation complex [nucleoplasm] (REACT_3018), Stalled Pol II in TC-NER [nucleoplasm] (REACT_4443), RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Open Promoter Complex [nucleoplasm] (REACT_3405), RNA Polymerase III Holoenzyme [nucleoplasm] (REACT_4447), Spliceosomal active C complex with lariat containing, 5-end cleaved pre-mRNP:CBC complex [nucleoplasm] (REACT_5191), Aborted early elongation complex [nucleoplasm] (REACT_3362), RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (REACT_4593), capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] (REACT_3243), HIV-1 Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm] (REACT_6503), HIV-1 elongation complex [nucleoplasm] (REACT_6501), RNA Polymerase II holoenzyme complex (generic) [nucleoplasm] (REACT_12944), Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (REACT_2410), RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (REACT_6426), ATAC C Complex with lariat containing 5-end cleaved mRNA [nucleoplasm] (REACT_5134), Tat-containing early elongation complex with hyperphosphorylated Pol II CTD ( phospho-NELF phospho DSIF) [nucleoplasm] (REACT_6633), HIV-1 transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (REACT_6638), Capping complex (GpppN..) [nucleoplasm] (REACT_2312), Active Pol II complex with repaired DNA template:mRNA hybrid [nucleoplasm] (REACT_2462), Covalent CE:GMP intermediate complex [nucleoplasm] (REACT_2774), pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (REACT_2469), pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (REACT_3251), HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (REACT_6450), HIV-1 initiation complex [nucleoplasm] (REACT_6518), HIV-1 Tat-containing processive elongation complex [nucleoplasm] (REACT_6452), HIV-1 paused processive elongation complex [nucleoplasm] (REACT_6459), HIV-1 transcription complex containing transcript to +30 [nucleoplasm] (REACT_6514), HIV-1 transcription complex containing extruded transcript to +30 [nucleoplasm] (REACT_6516), pol II transcription complex [nucleoplasm] (REACT_2954), Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (REACT_4544), Spliceosomal E Complex [nucleoplasm] (REACT_4545), Tat-containing elongation complex prior to separation [nucleoplasm] (REACT_6548), ATAC A Complex [nucleoplasm] (REACT_4037), RNA Polymerase III Closed SUP4 tRNATyr Promoter Complex [nucleoplasm] (REACT_5808), pol II closed pre-initiation complex [nucleoplasm] (REACT_5734), pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (REACT_3928), Aborted HIV-1 early elongation complex [nucleoplasm] (REACT_6695), HIV-1 transcription complex containing 9 nucleotide long transcript [nucleoplasm] (REACT_6561), HIV-1 transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (REACT_6563), Capping complex (initial) [nucleoplasm] (REACT_4555), RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (REACT_4790), HIV-1 elongation complex containing Tat [nucleoplasm] (REACT_6611), Pol II initiation complex [nucleoplasm] (REACT_5487), Early elongation complex with separated aborted transcript [nucleoplasm] (REACT_6590), Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (REACT_4335), DSIF:NELF:early elongation complex [nucleoplasm] (REACT_6594), HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (REACT_6640), Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (REACT_2481), Tat-containing early elongation complex with hyperphosphorylated Pol II CTD and phospho-NELF [nucleoplasm] (REACT_6495), RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (REACT_5819), pol II open pre-initiation complex [nucleoplasm] (REACT_4930), ATAC C Complex [nucleoplasm] (REACT_4626), P-TEFb(Cyclin T1:Cdk9)-containing elongation complex with separated and uncleaved transcript [nucleoplasm] (REACT_6686), HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (REACT_6680), HIV-1 processive elongation complex [nucleoplasm] (REACT_6579), HIV-1 aborted elongation complex after arrest [nucleoplasm] (REACT_6471), post exon ligation complex [nucleoplasm] (REACT_5793), RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Open Promoter Complex [nucleoplasm] (REACT_2429), RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm] (REACT_3935), HIV-1 arrested processive elongation complex [nucleoplasm] (REACT_6609), HIV-1 open pre-initiation complex [nucleoplasm] (REACT_6605), Pol II transcription complex containing transcript to +30 [nucleoplasm] (REACT_4399), HIV-1 Tat-containing aborted elongation complex after arrest [nucleoplasm] (REACT_6602), capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (REACT_3634), ATAC B Complex [nucleoplasm] (REACT_5095), RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (REACT_4417), CE:Pol II CTD:Spt5 complex [nucleoplasm] (REACT_2332), pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (REACT_4148), RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (REACT_4655), RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (REACT_5658), RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Promoter Complex [nucleoplasm] (REACT_5655), HIV-1 capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] (REACT_6374), HIV-1 promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex* [nucleoplasm] (REACT_6371), RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (REACT_3841), HIV-1 early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (REACT_6467), Paused processive elongation complex [nucleoplasm] (REACT_3066), RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (REACT_3694), Exon Junction Complex [nucleoplasm] (REACT_2984), DSIF:NELF:early elongation complex [nucleoplasm] (REACT_4575), RNA Polymerase III Terminator Paused Complex [nucleoplasm] (REACT_4574), Elongation complex [nucleoplasm] (REACT_3511), pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (REACT_4404), Active Pol II transcription complex with damaged DNA hybrid [nucleoplasm] (REACT_3609), capped, methylated pre-mRNP:CBC complex [nucleoplasm] (REACT_2736), RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (REACT_5870).
biological_process: termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription-coupled nucleotide-excision repair, DNA repair, nucleotide-excision repair, nuclear mRNA splicing, via spliceosome, viral transcription, mRNA capping, transcription initiation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter, positive regulation of viral transcription, RNA splicing, gene expression, viral reproduction.
These properties come from kegg analysis
KEGG_REACTION: ATP:polynucleotide (R00435), GTP:RNA (R00441), CTP:RNA (R00442), UTP:RNA (R00443).
molecular_function: DNA-directed RNA polymerase activity.
COG: DNA-directed RNA polymerase, subunit H, RpoH/RPB5 (COG2012).
