Protein coding gene MELO3C020474
Accession: MELO3C020474
Name: MELO3C020474
Description: Similar to Probable RNA polymerase II transcription factor B subunit 1-1 (Arabidopsis thaliana) (uniprot_sprot:sp|Q3ECP0|TFB1A_ARATH)
Properties
These properties come from reactome analysis
REACTOME_PATHWAY: RNA Polymerase II Transcription (REACT_99228), Dual incision reaction in TC-NER (REACT_109190), Dual incision reaction in GG-NER (REACT_90961), mRNA Capping (REACT_81603), Dual incision reaction in GG-NER (REACT_311), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_1655), DNA Repair (REACT_82907), RNA Pol II CTD phosphorylation and interaction with CE (REACT_96584), Formation of incision complex in GG-NER (REACT_257), Nucleotide Excision Repair (REACT_96106), Formation of transcription-coupled NER (TC-NER) repair complex (REACT_1941), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_78187), Global Genomic NER (GG-NER) (REACT_103919), RNA Polymerase I Transcription (REACT_1309), RNA Polymerase II HIV-1 Promoter Escape (REACT_6253), Formation of the Early Elongation Complex (REACT_846), HIV Life Cycle (REACT_6256), Formation of HIV-1 elongation complex in the absence of HIV-1 Tat (REACT_22201), RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (REACT_102763), RNA Polymerase I Transcription (REACT_110625), Transcription (REACT_1788), Gene Expression (REACT_85241), mRNA Capping (REACT_1470), RNA Polymerase I Chain Elongation (REACT_2204), RNA Polymerase I Chain Elongation (REACT_86256), Global Genomic NER (GG-NER) (REACT_92144), RNA Pol II CTD phosphorylation and interaction with CE (REACT_30624), RNA Polymerase I Promoter Escape (REACT_94173), RNA Polymerase II Transcription Elongation (REACT_92836), RNA Polymerase I Promoter Clearance (REACT_1974), Formation of the HIV-1 Early Elongation Complex (REACT_6319), RNA Polymerase II Promoter Escape (REACT_81662), RNA Polymerase II Promoter Escape (REACT_2089), RNA Polymerase I Transcription Termination (REACT_1074), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_109232), mRNA Processing (REACT_29019), RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription (REACT_21352), Transcription (REACT_93622), mRNA Capping (REACT_93735), Formation and Maturation of mRNA Transcript (REACT_77979), RNA Polymerase II Transcription (REACT_97471), mRNA Processing (REACT_109337), RNA Polymerase II Transcription (REACT_1366), RNA Polymerase II Pre-transcription Events (REACT_91707), Global Genomic NER (GG-NER) (REACT_2253), RNA Polymerase II Transcription Elongation (REACT_94090), RNA Polymerase I Promoter Escape (REACT_1913), RNA Polymerase II Promoter Escape (REACT_32829), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_85257), Formation of RNA Pol II elongation complex (REACT_1845), Transcription of the HIV genome (REACT_6233), RNA Pol II CTD phosphorylation and interaction with CE (REACT_6237), HIV-1 Transcription Initiation (REACT_6332), RNA Pol II CTD phosphorylation and interaction with CE (REACT_975), RNA Polymerase II Promoter Escape (REACT_106149), Formation and Maturation of mRNA Transcript (REACT_92291), Formation of the Early Elongation Complex (REACT_97522), DNA Repair (REACT_216), Gene Expression (REACT_91657), HIV Infection (REACT_6185), RNA Polymerase II Transcription Initiation (REACT_1851), RNA Polymerase II Pre-transcription Events (REACT_22107), Formation of incision complex in GG-NER (REACT_82554), Transcription-coupled NER (TC-NER) (REACT_29721), Nucleotide Excision Repair (REACT_106982), Formation of HIV-1 elongation complex containing HIV-1 Tat (REACT_6346), RNA Polymerase II Transcription Initiation (REACT_88340), RNA Polymerase II Transcription Elongation (REACT_107633), RNA Polymerase II Transcription Initiation (REACT_105389), Gene Expression (REACT_71), Formation of incision complex in GG-NER (REACT_83576), mRNA Processing (REACT_1675), Transcription (REACT_100899), Dual incision reaction in TC-NER (REACT_94657), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_98915), Dual incision reaction in GG-NER (REACT_91383), RNA Pol II CTD phosphorylation and interaction with CE (REACT_28314), Dual incision reaction in GG-NER (REACT_102444), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_28862), RNA Polymerase I Transcription Initiation (REACT_953), Nucleotide Excision Repair (REACT_1826), Nucleotide Excision Repair (REACT_77033), DNA Repair (REACT_107446), mRNA Capping (REACT_85081), Late Phase of HIV Life Cycle (REACT_6361), Dual incision reaction in TC-NER (REACT_91002), RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (REACT_79444), Gene Expression (REACT_105649), RNA Polymerase II Transcription (REACT_89454), Global Genomic NER (GG-NER) (REACT_88746), Dual incision reaction in TC-NER (REACT_2222), Transcription-coupled NER (TC-NER) (REACT_1628), Transcription (REACT_99758), RNA Polymerase II Transcription Initiation And Promoter Clearance (REACT_834), RNA Polymerase II Pre-transcription Events (REACT_91410), Formation of the Early Elongation Complex (REACT_29380), Tat-mediated elongation of the HIV-1 transcript (REACT_6162), Formation and Maturation of mRNA Transcript (REACT_2039), RNA Polymerase I Promoter Clearance (REACT_80486), RNA Polymerase II Transcription Elongation (REACT_833), RNA Polymerase II Transcription Initiation (REACT_104036), mRNA Processing (REACT_94551), DNA Repair (REACT_88201), Transcription-coupled NER (TC-NER) (REACT_93719), Formation and Maturation of mRNA Transcript (REACT_85219), Formation of the Early Elongation Complex (REACT_84349), Transcription-coupled NER (TC-NER) (REACT_96116), RNA Polymerase II Pre-transcription Events (REACT_99660), HIV-1 Transcription Elongation (REACT_6274), Formation of incision complex in GG-NER (REACT_30166).
REACTOME_REACTION: Phosphorylation (Ser5) of RNA pol II CTD (REACT_31984), 5-incision of DNA by ERCC1-XPF in GG-NER (REACT_1311), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_1251), RNA Polymerase II Promoter Opening: First Transition (REACT_80107), Abortive Initiation After Second Transition (REACT_1793), RNA Polymerase II Promoter Opening: First Transition (REACT_93391), Abortive initiation after formation of the first phosphodiester bond (REACT_32630), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_1467), Phosphorylation (Ser5) of RNA pol II CTD (REACT_88766), 3- incision of DNA by XPG in GG-NER (REACT_1124), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_1082), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_28192), Binding of ERCC1-XPF to preincision complex (REACT_99635), Recruitment of repair factors to form preincision complex (REACT_1492), Abortive HIV-1 Initiation After Second Transition (REACT_6265), Extrusion of 5-end of 30 nt long HIV-1 transcript through the pore in Pol II complex (REACT_6148), Formation of the closed pre-initiation complex (REACT_91116), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_94470), Fall Back to Closed Pre-initiation Complex (REACT_98220), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_88577), Methylation of GMP-cap by RNA Methyltransferase (REACT_97945), Dissociation of transcript with 5-GMP from GT (REACT_87469), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_99814), 3- incision of DNA by XPG in GG-NER (REACT_92894), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_102473), Binding of ERCC1-XPF to preincision complex (REACT_101859), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_34583), Methylation of GMP-cap by RNA Methyltransferase (REACT_404), Formation of open bubble structure in DNA by helicases (REACT_101644), Formation of the closed pre-initiation complex (REACT_632), Binding of ERCC1-XPF to preincision complex (REACT_2163), Formation of the closed pre-initiation complex (REACT_83351), 3 incision of the lesioned strand of DNA in TC-NER (REACT_80967), Elongation of pre-rRNA transcript (REACT_872), Addition of nucleotides between position +11 and +30 on HIV-1 transcript (REACT_6240), Dissociation of transcript with 5-GMP from GT (REACT_101219), Methylation of GMP-cap by RNA Methyltransferase (REACT_96650), Nucleophillic Attack by 3-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (REACT_88546), 3 incision of the lesioned strand of DNA in TC-NER (REACT_1274), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_81068), 5 incision leading to excision of DNA fragment with lesion in TC-NER (REACT_31823), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_1567), Fall Back to Closed Pre-initiation Complex (REACT_1702), Assembly of repair proteins at the site of Pol II blockage (REACT_1584), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_1968), Addition of Nucleotides 5 through 9 on the growing Transcript (REACT_100344), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_1368), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_33423), Recruitment of elongation factors to form HIV-1 elongation complex (REACT_6358), Addition of Nucleotides 5 through 9 on the growing Transcript (REACT_581), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_108808), Displacement of stalled Pol II from the lesion site (REACT_1284), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_423), Fall Back to Closed Pre-initiation Complex (REACT_86577), RNA Polymerase II Promoter Opening: First Transition (REACT_1844), 5 incision leading to excision of DNA fragment with lesion in TC-NER (REACT_94592), Loss of Rrn3 from RNA Polymerase I promoter escape complex (REACT_100182), Phosphorylation (Ser5) of RNA pol II CTD (REACT_6234), Newly formed phosphodiester bond stabilized and PPi released (REACT_6333), HIV-1 Promoter Opening: First Transition (REACT_6134), 5 incision leading to excision of DNA fragment with lesion in TC-NER (REACT_31162), RNA Polymerase II Promoter Opening: First Transition (REACT_89694), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_86293), Formation of the closed pre-initiation complex (REACT_105039), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_81891), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_103086), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_1055), Activation of GT (REACT_893), PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (REACT_211), Abortive initiation after formation of the first phosphodiester bond (REACT_653), Capping complex formation (REACT_86608), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_103482), Displacement of stalled Pol II from the lesion site (REACT_103124), NTP Binds Active Site of RNA Polymerase II (REACT_106132), Addition of nucleotides between position +11 and +30 (REACT_28303), Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (REACT_513), 3 incision of the lesioned strand of DNA in TC-NER (REACT_92741), NTP Binds Active Site of RNA Polymerase II (REACT_1160), Addition of nucleotides leads to transcript elongation (REACT_751), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_6220), NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex (REACT_6349), Formation of the CE:GMP intermediate complex (REACT_110689), Addition of nucleotides between position +11 and +30 (REACT_28970), Recruitment of elongation factors to form elongation complex (REACT_949), Abortive HIV-1 initiation after formation of the first phosphodiester bond (REACT_6226), Methylation of GMP-cap by RNA Methyltransferase (REACT_93915), Transfer of GMP from the capping enzyme GT site to 5-end of mRNA (REACT_77279), Activation of GT (REACT_6298), Formation of the CE:GMP intermediate complex (REACT_101635), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_6295), Formation of open bubble structure in DNA by helicases (REACT_95993), Activation of GT (REACT_103525), Phosphorylation (Ser5) of RNA pol II CTD (REACT_77857), Addition of nucleotides between position +11 and +30 (REACT_209), 3- incision of DNA by XPG in GG-NER (REACT_81714), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_2233), Formation of the CE:GMP intermediate complex (REACT_1580), Capping complex formation (REACT_77633), Hydrolysis of the 5-end of the nascent transcript by the capping enzyme (REACT_85239), Dissociation of transcript with 5-GMP from GT (REACT_106203), Formation of open bubble structure in DNA by helicases (REACT_78462), Fall Back to Closed Pre-initiation Complex (REACT_6211), Addition of nucleotides between position +11 and +30 (REACT_77879), 5 incision leading to excision of DNA fragment with lesion in TC-NER (REACT_811), Abortive Initiation After Second Transition (REACT_103184), Addition of nucleotides leads to transcript elongation (REACT_100466), Formation of open bubble structure in DNA by helicases (REACT_1033), 3- incision of DNA by XPG in GG-NER (REACT_100654), Capping complex formation (REACT_2186), NTP Binds Active Site of RNA Polymerase II (REACT_80120), Nucleophillic attack by 3-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (REACT_6285), Formation of the CE:GMP intermediate complex (REACT_92552), Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box (REACT_2228), Loss of Rrn3 from RNA Polymerase I promoter escape complex (REACT_373), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_96127), Activation of GT (REACT_96305), Phosphorylation (Ser5) of RNA pol II CTD (REACT_1185), Displacement of stalled Pol II from the lesion site (REACT_28718), Displacement of stalled Pol II from the lesion site (REACT_108076), Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition (REACT_6208), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_92765), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_85925), Abortive Initiation Before Second Transition (REACT_106763), 3 incision of the lesioned strand of DNA in TC-NER (REACT_106756), Abortive HIV-1 Initiation Before Second Transition (REACT_6203), Elongation of pre-rRNA transcript (REACT_102951), Fall Back to Closed Pre-initiation Complex (REACT_100253), Hypophosphorylation of RNA Pol II CTD by FCP1P protein (REACT_6206), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_105022), Extrusion of 5-end of 30 nt long transcript through the pore in Pol II complex (REACT_87062), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_100578), NTP Binds Active Site of RNA Polymerase II (REACT_80520), Activation of GT (REACT_106797), Capping complex formation (REACT_91663), Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (REACT_29681), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_109877), Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (REACT_139), Binding of ERCC1-XPF to preincision complex (REACT_105931), SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (REACT_108201), RNA Polymerase II CTD (phosphorylated) binds to CE (REACT_84917), Addition of nucleotides 5 through 9 on the growing HIV-1 transcript (REACT_6172), Newly Formed Phosphodiester Bond Stabilized and PPi Released (REACT_86674), Addition of nucleotides leads to HIV-1 transcript elongation (REACT_6278), Recruitment of elongation factors to form HIV-1 elongation complex (REACT_6275), Abortive Initiation Before Second Transition (REACT_543), Dissociation of transcript with 5-GMP from GT (REACT_703).
REACTOME_COMPLEX: HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (REACT_6450), HIV-1 initiation complex [nucleoplasm] (REACT_6518), HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (REACT_6680), RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (REACT_6521), Capping complex (intermediate) [nucleoplasm] (REACT_3580), Pol II Promoter Escape Complex [nucleoplasm] (REACT_3851), Capping complex (hydrolyzed) [nucleoplasm] (REACT_4969), HIV-1 transcription complex containing transcript to +30 [nucleoplasm] (REACT_6514), HIV-1 transcription complex containing extruded transcript to +30 [nucleoplasm] (REACT_6516), PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (REACT_4203), RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (REACT_3171), pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (REACT_5212), HIV-1 closed pre-initiation complex [nucleoplasm] (REACT_6553), RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (REACT_2713), Pol II transcription complex containing transcript to +30 [nucleoplasm] (REACT_4399), TFIIH [nucleoplasm] (REACT_3832), HIV-1 elongation complex containing Tat [nucleoplasm] (REACT_6611), HIV-1 transcription complex [nucleoplasm] (REACT_6433), CE:Pol II CTD:Spt5 complex [nucleoplasm] (REACT_2332), Incision complex with 3-incised damaged DNA [nucleoplasm] (REACT_5099), RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (REACT_6659), pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (REACT_4148), RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (REACT_4655), Capping complex (GpppN..) [nucleoplasm] (REACT_2312), RNA Polymerase I promoter escape complex [nucleoplasm] (REACT_5158), HIV-1 Promoter Escape Complex [nucleoplasm] (REACT_6417), pol II closed pre-initiation complex [nucleoplasm] (REACT_5734), HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (REACT_6640), Elongation complex [nucleoplasm] (REACT_3511), pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (REACT_3183), pre-incision complex with open DNA bubble [nucleoplasm] (REACT_5689), Transcription-coupled (TC) repair complex [nucleoplasm] (REACT_3969), pre-incision complex in GG-NER [nucleoplasm] (REACT_5795), HIV-1 elongation complex [nucleoplasm] (REACT_6501), RNA Polymerase I Transcription Initiation complex [nucleoplasm] (REACT_4081), incision complex for GG-NER [nucleoplasm] (REACT_5159), HIV-1 transcription complex containing 9 nucleotide long transcript [nucleoplasm] (REACT_6561), HIV-1 transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (REACT_6563), Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (REACT_2410), HIV-1 open pre-initiation complex [nucleoplasm] (REACT_6605), Capping complex (initial) [nucleoplasm] (REACT_4555), RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (REACT_2371), HIV-1 transcription complex containing 11 nucleotide long transcript [nucleoplasm] (REACT_6664), HIV-1 transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (REACT_6638), Pol II initiation complex [nucleoplasm] (REACT_5487), pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (REACT_3928), Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (REACT_2595), Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (REACT_4335), CE:Pol II CTD:Spt5 complex [nucleoplasm] (REACT_6491), pol II transcription complex [nucleoplasm] (REACT_2954), Covalent CE:GMP intermediate complex [nucleoplasm] (REACT_2774), pol II open pre-initiation complex [nucleoplasm] (REACT_4930), Capping complex (with freed 5- GMP) [nucleoplasm] (REACT_4741), pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (REACT_3251).
biological_process: nucleotide-excision repair, DNA damage removal, DNA repair, transcription-coupled nucleotide-excision repair, transcription initiation from RNA polymerase I promoter, transcription elongation from RNA polymerase I promoter, termination of RNA polymerase I transcription, transcription initiation from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter, mRNA capping, viral reproduction, positive regulation of viral transcription, gene expression, nucleotide-excision repair, viral transcription, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter.
These properties come from phylome analysis
molecular_function: protein binding, general RNA polymerase II transcription factor activity.
cellular_component: nucleus, holo TFIIH complex.
biological_process: regulation of cyclin-dependent protein kinase activity, nucleotide-excision repair, DNA damage removal, DNA repair, transcription-coupled nucleotide-excision repair, transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase I promoter, transcription elongation from RNA polymerase I promoter, termination of RNA polymerase I transcription, transcription initiation from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter, mRNA capping, viral reproduction, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription.
These properties come from kegg analysis
KEGG_ORTHOLOGS: transcription initiation factor TFIIH subunit 1 (K03141).
molecular_function: general RNA polymerase II transcription factor activity.
