Protein coding gene MELO3C021058

Accession: MELO3C021058

Name: MELO3C021058

Description: Similar to Cell division control protein 45 homolog (Schizosaccharomyces pombe) (uniprot_sprot:sp|O74113|CDC45_SCHPO)

Properties

These properties come from blast2go analysis


cellular_component: nucleus.

biological_process: DNA-dependent DNA replication initiation.

These properties come from reactome analysis


REACTOME_REACTION: Cdc45 associates with the pre-replicative complex at the origin (REACT_31079), Multiple proteins are localized at replication fork (REACT_6963), Cdc45 associates with the pre-replicative complex at the origin (REACT_83433), Multiple proteins are localized at replication fork (REACT_83344), Multiple proteins are localized at replication fork (REACT_93102), Loading of claspin onto DNA during replication origin firing (REACT_6738), DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (REACT_95886), Loading of claspin onto DNA during replication origin firing (REACT_89725), DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (REACT_789), Multiple proteins are localized at replication fork (REACT_28298), Activation of claspin (REACT_6750), Cdc45 associates with the pre-replicative complex at the origin (REACT_108604), Cdc45 associates with the pre-replicative complex at the origin (REACT_135), Multiple proteins are localized at replication fork (REACT_77137), Multiple proteins are localized at replication fork (REACT_94448).

biological_process: cell cycle checkpoint, mitotic cell cycle, DNA replication, G1/S transition of mitotic cell cycle, DNA strand elongation involved in DNA replication, M/G1 transition of mitotic cell cycle, S phase of mitotic cell cycle.

REACTOME_COMPLEX: Unwinding complex at replication fork [nucleoplasm] (REACT_7007), Cdc45:CDK:DDK:Mcm10:pre-replicative complex [nucleoplasm] (REACT_4546), Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (REACT_7262), Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (REACT_7273), RPA:Cdc45:CDK:DDK:Mcm10:pre-replicative complex [nucleoplasm] (REACT_2568).

REACTOME_PATHWAY: Synthesis of DNA (REACT_29939), Mitotic M-M/G1 phases (REACT_82114), Activation of the pre-replicative complex (REACT_83196), Synthesis of DNA (REACT_31294), DNA Replication (REACT_106731), Activation of the pre-replicative complex (REACT_89455), DNA strand elongation (REACT_85667), S Phase (REACT_82813), DNA Replication (REACT_383), Cell Cycle Checkpoints (REACT_109101), Unwinding of DNA (REACT_93501), Activation of the pre-replicative complex (REACT_1095), DNA strand elongation (REACT_107311), M/G1 Transition (REACT_79481), Mitotic G1-G1/S phases (REACT_21267), Activation of ATR in response to replication stress (REACT_108929), Unwinding of DNA (REACT_91767), Cell Cycle, Mitotic (REACT_152), Unwinding of DNA (REACT_6776), G1/S Transition (REACT_1783), G2/M Checkpoints (REACT_86653), Unwinding of DNA (REACT_98532), Mitotic M-M/G1 phases (REACT_21300), Mitotic M-M/G1 phases (REACT_95347), S Phase (REACT_89318), DNA Replication Pre-Initiation (REACT_99126), M/G1 Transition (REACT_32146), Cell Cycle, Mitotic (REACT_85950), Unwinding of DNA (REACT_100553), Synthesis of DNA (REACT_29575), DNA Replication Pre-Initiation (REACT_88865), G2/M Checkpoints (REACT_828), Activation of the pre-replicative complex (REACT_110126), Mitotic G1-G1/S phases (REACT_93079), S Phase (REACT_81914), DNA Replication Pre-Initiation (REACT_734), Mitotic M-M/G1 phases (REACT_88420), Synthesis of DNA (REACT_2014), Mitotic G1-G1/S phases (REACT_82281), Cell Cycle, Mitotic (REACT_84794), G1/S Transition (REACT_102687), Cell Cycle Checkpoints (REACT_1538), DNA strand elongation (REACT_84115), S Phase (REACT_105829), M/G1 Transition (REACT_83776), S Phase (REACT_34043), G1/S Transition (REACT_109784), M/G1 Transition (REACT_1725), Cell Cycle, Mitotic (REACT_108233), DNA strand elongation (REACT_84140), DNA Replication (REACT_101785), DNA Replication (REACT_85544), S Phase (REACT_899), DNA Replication (REACT_102375), Synthesis of DNA (REACT_77553), Cell Cycle, Mitotic (REACT_90846), DNA Replication (REACT_96557), DNA Replication Pre-Initiation (REACT_32026), Unwinding of DNA (REACT_105674), G1/S Transition (REACT_87037), DNA strand elongation (REACT_83094), Synthesis of DNA (REACT_98237), Activation of ATR in response to replication stress (REACT_6769), DNA strand elongation (REACT_932), Cell Cycle, Mitotic (REACT_96281), Mitotic G1-G1/S phases (REACT_109527).

These properties come from phylome analysis


molecular_function: protein binding, binding, DNA replication origin binding, chromatin binding.

cellular_component: replication fork protection complex, DNA replication preinitiation complex, centrosome, cytoplasm, pre-replicative complex, nucleoplasm.

biological_process: cell division, gametophyte development, positive regulation of S phase of mitotic cell cycle, regulation of chromatin silencing at telomere, chromosome condensation, embryo development ending in birth or egg hatching, mitotic cell cycle G2/M transition DNA damage checkpoint, cell cycle, premeiotic DNA replication, DNA amplification, DNA strand elongation involved in DNA replication, pre-replicative complex assembly, double-strand break repair via break-induced replication, M/G1 transition of mitotic cell cycle, S phase of mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle, DNA replication checkpoint, DNA-dependent DNA replication initiation.

These properties come from kegg analysis


KEGG_ORTHOLOGS: cell division control protein 45 (K06628).

Locations

Located in CM3.5_scaffold00046 from 1565040 to 1567063.

Related features