Polypeptide MELO3C021247P1
Accession: MELO3C021247P1
Name: MELO3C021247P1
Description: Similar to Dihydrolipoyl dehydrogenase 1, mitochondrial (Arabidopsis thaliana) (uniprot_sprot:sp|Q9M5K3|DLDH1_ARATH)
Sequence:
>MELO3C021247P1 Similar to Dihydrolipoyl dehydrogenase 1, mitochondrial (Arabidopsis thaliana) (uniprot_sprot:sp|Q9M5K3|DLDH1_ARATH) MALAICARRKANLLYRNLPLSSSESFNYSFSFASFSRRFASSGFDDNDVVVIGGGPGGYVAAIKAAQLGLKTTCIEKRGA LGGTCLNVGCIPSKALLHSSHMYHEAQHSFASHGVKFSSLEVDLPAMMAQKDKAVSNLTRGIEGLFKKNKVNYVKGYGKL ISPSEVSVDTIDGGNTVVKGKNIIIATGSDVKSLPGITIDEKRIVSSTGALALSEIPKKLVVIGAGYIGLEMGSVWGRLG SEITVVEFAPDIVPTMDGEVRKQFQRSLEKQGMKFMLRTKVVGVDTSGNGVKLTLEPAAGGEQTTLEADVVLVSAGRTPF TAGLGLDKLGIETDKAGRILVNERFATNVDGVYAIGDVIPGPMLAHKAEEDGVACVEFLAGKTGHVDYDKVPGVVYTHPE VASVGKTEEQVKESGVDYRVGKFPFLANSRAKAIDDAEGVVKILAEKETDKILGVHIMAPNAGELIHEAVLALQYDAASE DIARVCHAHPTMSEALKEAAMATYDKPIHI*
Download fasta sequence.
Properties
These properties come from blast2go analysis
molecular_function: flavin adenine dinucleotide binding, ATP binding, protein binding, dihydrolipoyl dehydrogenase activity.
cellular_component: apoplast, glycine cleavage complex, mitochondrial matrix.
biological_process: oxidation-reduction process, response to cadmium ion, cell redox homeostasis.
These properties come from reactome analysis
REACTOME_REACTION: a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+ (REACT_1813), a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+ (REACT_30155), pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (REACT_95829), pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (REACT_983), alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (REACT_97909), a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+ (REACT_101696), PDP-catalyzed dephosphorylation (activation) of phospho E1 alpha subunit (REACT_12543), PDP-catalyzed dephosphorylation (activation) of phospho E1 alpha subunit (REACT_101860), pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (REACT_102641), PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit (REACT_12462), pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (REACT_96649), alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (REACT_1865), pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (REACT_108497), alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (REACT_66), alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (REACT_91421), a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+ (REACT_30883), a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+ (REACT_34280), alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (REACT_79126), alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (REACT_89895), PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit (REACT_91743).
biological_process: branched chain family amino acid catabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, cellular nitrogen compound metabolic process, lysine catabolic process, pyruvate metabolic process, tricarboxylic acid cycle.
REACTOME_COMPLEX: alpha-keto acid dehydrogenase E3 holoenzyme [mitochondrial matrix] (REACT_3390), alpha-ketoglutarate dehydrogenase complex [mitochondrial matrix] (REACT_5646), phosphorylated pyruvate dehydrogenase complex [mitochondrial matrix] (REACT_12644), alpha-keto acid dehydrogenase E3 homodimer [mitochondrial matrix] (REACT_5578), branched-chain alpha-ketoacid dehydrogenase complex [mitochondrial matrix] (REACT_3604), pyruvate dehydrogenase complex [mitochondrial matrix] (REACT_5500).
REACTOME_PATHWAY: Metabolism of amino acids and derivatives (REACT_90299), Branched-chain amino acid catabolism (REACT_82706), Pyruvate metabolism (REACT_93569), Metabolism of amino acids and derivatives (REACT_107293), Lysine catabolism (REACT_82423), Pyruvate metabolism (REACT_78738), Pyruvate metabolism and Citric Acid (TCA) cycle (REACT_91911), Branched-chain amino acid catabolism (REACT_87459), Branched-chain amino acid catabolism (REACT_93183), Pyruvate metabolism and Citric Acid (TCA) cycle (REACT_105165), Branched-chain amino acid catabolism (REACT_89793), Metabolism of amino acids and derivatives (REACT_28699), Pyruvate metabolism and Citric Acid (TCA) cycle (REACT_93980), Pyruvate metabolism and Citric Acid (TCA) cycle (REACT_30825), Citric acid cycle (TCA cycle) (REACT_1785), Branched-chain amino acid catabolism (REACT_197), Pyruvate metabolism and Citric Acid (TCA) cycle (REACT_1046), Metabolism of amino acids and derivatives (REACT_13), Regulation of pyruvate dehydrogenase (PDH) complex (REACT_12528), Pyruvate metabolism (REACT_2071), Citric acid cycle (TCA cycle) (REACT_81042), Citric acid cycle (TCA cycle) (REACT_83116), Metabolism of amino acids and derivatives (REACT_86268), Lysine catabolism (REACT_29109), Metabolism of amino acids and derivatives (REACT_29108), Pyruvate metabolism (REACT_104471), Pyruvate metabolism and Citric Acid (TCA) cycle (REACT_28892), Pyruvate metabolism (REACT_100674), Lysine catabolism (REACT_1298), Regulation of pyruvate dehydrogenase (PDH) complex (REACT_95852).
These properties come from phylome analysis
molecular_function: flavin adenine dinucleotide binding, dihydrolipoyl dehydrogenase activity.
cellular_component: cytoplasm.
biological_process: oxidation-reduction process, cell redox homeostasis.
These properties come from kegg analysis
KEGG_REACTION: enzyme (R07618), dihydrolipoylprotein:NAD+ (R03815), Dihydrolipoamide:NAD+ (R01698).
molecular_function: dihydrolipoyl dehydrogenase activity.
This polypeptide in other databases
In PhylomeDB is Phy003A45E_CUCME .
