Protein coding gene MELO3C022725

Accession: MELO3C022725

Name: MELO3C022725

Description: Similar to E3 ubiquitin-protein ligase CHIP (Arabidopsis thaliana) (uniprot_sprot:sp|Q9SRS9|CHIP_ARATH)


These properties come from blast2go analysis

molecular_function: binding, ubiquitin-protein ligase activity.

cellular_component: ubiquitin ligase complex.

biological_process: protein ubiquitination, response to stress.

These properties come from reactome analysis

REACTOME_REACTION: Interaction of E3 with substrate and E2-Ub complex (REACT_75856), Transfer of Ub from E2 to substrate and release of E2 (REACT_75901), Release of E3 from polyubiquitinated substrate (REACT_75928).

biological_process: antigen processing and presentation of peptide antigen via MHC class I, protein polyubiquitination.

REACTOME_COMPLEX: E3:Ub:substrate [cytosol] (REACT_76185), E3:K48-polyubiquitinated substrate [cytosol] (REACT_75972), Ag-substrate:E3:E2:Ub [cytosol] (REACT_76727).

REACTOME_PATHWAY: Adaptive Immunity Signaling (REACT_75774), Antigen processing: Ubiquitination & Proteasome degradation (REACT_75842), Immune System (REACT_6900), Class I MHC mediated antigen processing & presentation (REACT_75820).

These properties come from phylome analysis

molecular_function: Hsp90 protein binding, misfolded protein binding, chaperone binding, SMAD binding, protein homodimerization activity, ubiquitin-ubiquitin ligase activity, ubiquitin protein ligase binding, TPR domain binding, protein binding, bridging, Hsp70 protein binding, kinase binding, binding, ubiquitin-protein ligase activity.

cellular_component: nuclear inclusion body, ubiquitin conjugating enzyme complex, cytoplasm, ubiquitin ligase complex.

biological_process: positive regulation of cellular chaperone-mediated protein complex assembly, cellular response to misfolded protein, protein K63-linked ubiquitination, protein autoubiquitination, protein maturation, sarcomere organization, proteasomal ubiquitin-dependent protein catabolic process, locomotion, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, regulation of glucocorticoid metabolic process, positive regulation of protein ubiquitination, ubiquitin-dependent SMAD protein catabolic process, oviposition, response to abscisic acid stimulus, response to salt stress, response to temperature stimulus, misfolded or incompletely synthesized protein catabolic process, DNA repair, nematode larval development, protein polyubiquitination, response to stress.

These properties come from kegg analysis

KEGG_ORTHOLOGS: STIP1 homology and U-box containing protein 1 [EC:] (K09561).

molecular_function: Hsp90 protein binding, SMAD binding, TPR domain binding, Hsp70 protein binding.


Located in CM3.5_scaffold00054 from 1760916 to 1776007.

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