Protein coding gene MELO3C024028
Accession: MELO3C024028
Name: MELO3C024028
Description: Similar to Eukaryotic initiation factor 4A-3 (Nicotiana plumbaginifolia PE=2 SV=1) (uniprot_sprot:sp|P41380|IF4A3_NICPL)
Properties
These properties come from blast2go analysis
molecular_function: ATP-dependent helicase activity, ATP binding, protein binding, translation initiation factor activity, RNA binding.
cellular_component: exon-exon junction complex, nuclear speck, nucleolus.
biological_process: translation, mRNA processing, response to hypoxia.
These properties come from reactome analysis
REACTOME_REACTION: UPF1 Binds an mRNP with a Termination Codon Preceding an Exon Junction Complex (REACT_75753), SMG1 Phosphorylates UPF1 (Enhanced by Exon Junction Complex) (REACT_75910).
biological_process: mRNA metabolic process, RNA metabolic process.
REACTOME_COMPLEX: Exon Junction:UPF2:UPF3 Complex [cytosol] (REACT_76254), Core Exon Junction Complex (Core EJC) [cytosol] (REACT_76521), SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (REACT_76156), SMG1:UPF1:EJC:Translated mRNP [cytosol] (REACT_76647), Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (REACT_76510), Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (REACT_76275).
REACTOME_PATHWAY: Metabolism of RNA (REACT_21257), Nonsense-Mediated Decay (REACT_75886), Metabolism of mRNA (REACT_20605), Nonsense Mediated Decay Enhanced by the Exon Junction Complex (REACT_75822).
These properties come from phylome analysis
molecular_function: ATPase activity, uncoupled, poly(A) RNA binding, ATP-dependent RNA helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding, protein binding, RNA binding.
cellular_component: catalytic step 2 spliceosome, precatalytic spliceosome, pole plasm, cytoplasm, spliceosomal complex, exon-exon junction complex, nuclear speck, nucleolus.
biological_process: mRNA transport, positive regulation of translation, pole plasm oskar mRNA localization, negative regulation of translation, RNA splicing, response to DNA damage stimulus, rRNA processing, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), nuclear mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, mRNA processing.
These properties come from kegg analysis
KEGG_ORTHOLOGS: ATP-dependent RNA helicase [EC:3.6.4.13] (K13025).
molecular_function: ATP-dependent RNA helicase activity.
COG: Superfamily II DNA and RNA helicases (COG0513).
